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生长棒植入术改善早发性脊柱侧凸患者的营养状况：一项至少 3 年随访的病例系列研究。

Growing-rod implantation improves nutrition status of early-onset scoliosis patients: a case series study of minimum 3-year follow-up.

机构信息

Department of Orthopaedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Shuaifuyuan #1, Dongcheng District, Beijing, 100730, China.

Department of Orthopaedics, Peking University Fourth Clinical Medical College, Beijing Jishuitan Hospital, Beijing, 100035, China.

出版信息

BMC Surg. 2021 Mar 1;21(1):106. doi: 10.1186/s12893-021-01120-7.

DOI:10.1186/s12893-021-01120-7
PMID:33648467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7923317/
Abstract

BACKGROUND

Early onset scoliosis (EOS) may cause malnutrition in affected patients. Growing-rod treatment has been an effective protocol for treating EOS. The objective of this study is to demonstrate whether growing-rod treatment improves nutritional status of EOS patients.

METHODS

Fifty-two EOS patients who had dual growing-rod surgery was enrolled. The minimum follow-up was 3-years. Their body weights were normalized based on the data of two National Population Census of China. Z-scores were used to indicate the standard deviation from the median body weight-for-age.

RESULTS

The median follow-up time was 6 years. Preoperatively, the prevalence of malnutrition (Z < - 2) was 21.2%, and reduced to 9.6% at the end of the follow-up. Preoperatively, the average Z-score was - 0.94, and it increased to - 0.65 at the latest follow-up (p < 0.05). Patients with preoperative Z-score below - 1 had more significant increase of Z-scores (- 2.15 vs - 1.26, p < 0.001). A significant negative correlation between the change of Z-score and the preoperative Z-score (correlation coefficient - 0.65, p < 0.001).

CONCLUSIONS

The growing rod surgery and lengthening procedures significantly improves the nutrition status of EOS patients. The body weight gains are more significant in patients with lower body weights.

摘要

背景

早发性脊柱侧凸（EOS）可能导致患病患者营养不良。生长棒治疗已成为治疗 EOS 的有效方案。本研究旨在证明生长棒治疗是否能改善 EOS 患者的营养状况。

方法

52 名接受过双生长棒手术的 EOS 患者被纳入研究。随访时间至少为 3 年。他们的体重根据中国两次全国人口普查的数据进行标准化。Z 分数用于表示体重与年龄中位数的标准差。

结果

中位随访时间为 6 年。术前，营养不良（Z < -2）的患病率为 21.2%，随访结束时降至 9.6%。术前，平均 Z 分数为 -0.94，随访时增加至 -0.65（p < 0.05）。术前 Z 分数低于-1 的患者 Z 分数增加更为显著（-2.15 比-1.26，p < 0.001）。Z 分数变化与术前 Z 分数之间呈显著负相关（相关系数 -0.65，p < 0.001）。

结论

生长棒手术和延长术显著改善了 EOS 患者的营养状况。体重增加在体重较低的患者中更为显著。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9504/7923317/552535f3e52c/12893_2021_1120_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9504/7923317/437638158b32/12893_2021_1120_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9504/7923317/959a9816c135/12893_2021_1120_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9504/7923317/7fef1ea5c098/12893_2021_1120_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9504/7923317/552535f3e52c/12893_2021_1120_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9504/7923317/437638158b32/12893_2021_1120_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9504/7923317/959a9816c135/12893_2021_1120_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9504/7923317/7fef1ea5c098/12893_2021_1120_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9504/7923317/552535f3e52c/12893_2021_1120_Fig4_HTML.jpg

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