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本文引用的文献

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Pasteurella multocida Infections: I. Pasteurella Multocida Infection Due to Animal Bite.多杀巴斯德菌感染：一、动物咬伤所致多杀巴斯德菌感染
Am J Public Health Nations Health. 1970 Jun;60(6):1103-8. doi: 10.2105/ajph.60.6.1103.
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Pasteurella multocida infection in the hand.
Plast Reconstr Surg. 1981 Jan;67(1):49-53. doi: 10.1097/00006534-198101000-00011.
3
Dog bite wounds and infection: a prospective clinical study.犬咬伤伤口与感染：一项前瞻性临床研究。
Ann Emerg Med. 1980 Oct;9(10):508-12. doi: 10.1016/s0196-0644(80)80188-0.
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Characteristics of 20 human Pasteurella isolates from animal bite wounds.
Acta Pathol Microbiol Scand B. 1981 Jun;89(3):137-41. doi: 10.1111/j.1699-0463.1981.tb00166_89b.x.
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Pasteurella multocida. Osteomyelitis following dog bites.
Am J Dis Child. 1981 Jul;135(7):625-7. doi: 10.1001/archpedi.1981.02130310031011.
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Characteristics and biotypes of Pasteurella multocida isolated from humans.从人类分离出的多杀巴斯德菌的特征及生物型
J Clin Microbiol. 1981 Mar;13(3):566-71. doi: 10.1128/jcm.13.3.566-571.1981.
7
Prophylactic oxacillin in dog bite wounds.犬咬伤伤口的预防性苯唑西林治疗。
Ann Emerg Med. 1982 May;11(5):248-51. doi: 10.1016/s0196-0644(82)80093-0.
8
Prophylactic antibiotics in common dog bite wounds: a controlled study.常见犬咬伤伤口预防性使用抗生素：一项对照研究。
Ann Emerg Med. 1980 Aug;9(8):410-4. doi: 10.1016/s0196-0644(80)80153-3.
9
Evaluation of prophylactic oxacillin in cat bite wounds.猫咬伤伤口预防性使用苯唑西林的评估
Ann Emerg Med. 1984 Mar;13(3):155-7. doi: 10.1016/s0196-0644(84)80604-6.
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Pasteurella multocida infections. Report of 34 cases and review of the literature.多杀巴斯德菌感染。34例报告及文献复习
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某些头孢菌素、红霉素和苯唑西林的口服剂型对多杀巴斯德菌缺乏体外有效性。

Lack of in vitro efficacy of oral forms of certain cephalosporins, erythromycin, and oxacillin against Pasteurella multocida.

作者信息

Goldstein E J, Citron D M, Richwald G A

机构信息

R.M. Alden Research Laboratory, Santa Monica Hospital Medical Center, California 90404.

出版信息

Antimicrob Agents Chemother. 1988 Feb;32(2):213-5. doi: 10.1128/AAC.32.2.213.

DOI:10.1128/AAC.32.2.213
PMID:3364944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC172137/
Abstract

The in vitro susceptibility of human isolates of Pasteurella multocida to oral antimicrobial agents from our current study and from a review of the literature suggests that dicloxacillin (oxacillin), erythromycin, clindamycin, cephalexin, cefaclor, and cefadroxil should not be used for empiric therapy of animal bite wounds. Agents that were consistently active against P. multocida were penicillin, ampicillin, amoxicillin-clavulanic acid, tetracycline, minocycline, chloramphenicol, trimethoprim-sulfamethoxazole, and cefuroxime. Possible reasons for the confusion regarding the activity of oral cephalosporins are addressed.

摘要

从我们当前的研究以及文献综述来看，多杀巴斯德菌的人体分离株对口服抗菌药物的体外敏感性表明，双氯西林（苯唑西林）、红霉素、克林霉素、头孢氨苄、头孢克洛和头孢羟氨苄不应被用于动物咬伤伤口的经验性治疗。对多杀巴斯德菌始终有效的药物有青霉素、氨苄西林、阿莫西林-克拉维酸、四环素、米诺环素、氯霉素、甲氧苄啶-磺胺甲恶唑和头孢呋辛。文中探讨了口服头孢菌素活性方面存在混淆的可能原因。