• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新冠疫情时代的支气管类癌肿瘤:一例报告

Bronchial carcinoid tumor in the era of covid-19 pandemic: A case report.

作者信息

Mindaye Esubalew Taddese, Kassahun Mulugeta, Tigiye Gulilat

机构信息

Department of Surgery, Saint Paul's Hospital Millennium Medical College, Swaziland Street, 1271, Addis Ababa, Ethiopia.

Department of Surgery, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

出版信息

Int J Surg Case Rep. 2021 Mar;80:105703. doi: 10.1016/j.ijscr.2021.105703. Epub 2021 Feb 24.

DOI:10.1016/j.ijscr.2021.105703
PMID:33649715
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7903907/
Abstract

INTRODUCTION

Bronchial carcinoid tumors are rare, slow growing, malignant neuroendocrine tumors which arise from Enterochromaffin (Kulchitsky) cells. Early diagnosis is extremely important as the main stay of treatment is surgical excision.

PRESENTATION OF CASE

We present a rare case of bronchial typical carcinoid tumor in a 27-year-old male who presented with a complaint of intermittent dry cough of 2 weeks' duration associated with shortness of breath and low grade fever. He was initially misdiagnosed as covid-19 pneumonia and was admitted to covid-19 treatment center. Right lung bi-lobectomy with regional lymph node resection was done and he was discharged home in good condition.

DISCUSSION

Majority of typical carcinoids are located in the central airways leading to bronchial obstruction with recurrent pneumonia, chest pain and wheezing. In the era of covid-19 pandemic, lung cancer patients are at higher risk of being affected by covid-19 and, early identification and differential diagnosis is extremely difficult in the absence of comprehensive evaluation and work up as the clinical and imaging findings of covid-19 may resemble lung cancer. Although hilar and mediastinal lymph nodes are the most common metastatic sites for typical carcinoids most lymphadenopathies are caused by a reactive inflammatory reaction.

CONCLUSION

Bronchial carcinoids are rare, malignant neuroendocrine tumors with complete surgical resection being the only curative management. During the Covid-19 pandemic crisis, diagnosing rare lung diseases like carcinoid tumor is real challenge especially in resource limited set up and needs high index of suspicion with meticulous diagnostic work up. The outcome of typical carcinoids with lymph node metastasis is excellent with complete resection.

摘要

引言

支气管类癌是罕见的、生长缓慢的恶性神经内分泌肿瘤,起源于嗜银(库尔契茨基)细胞。由于主要治疗方法是手术切除,早期诊断极为重要。

病例介绍

我们报告一例罕见的支气管典型类癌病例,患者为一名27岁男性,主诉持续2周的间歇性干咳,伴有呼吸急促和低热。他最初被误诊为新冠病毒肺炎,并被收治于新冠病毒治疗中心。进行了右肺双叶切除术及区域淋巴结切除术,患者康复出院。

讨论

大多数典型类癌位于中央气道,导致支气管阻塞,出现反复肺炎、胸痛和喘息。在新冠疫情时代,肺癌患者感染新冠病毒的风险更高,在缺乏全面评估和检查的情况下,由于新冠病毒的临床和影像学表现可能与肺癌相似,早期识别和鉴别诊断极为困难。尽管肺门和纵隔淋巴结是典型类癌最常见的转移部位,但大多数淋巴结肿大是由反应性炎症引起的。

结论

支气管类癌是罕见的恶性神经内分泌肿瘤,完整手术切除是唯一的治愈性治疗方法。在新冠疫情危机期间,诊断类癌等罕见肺部疾病是一项真正的挑战,尤其是在资源有限的情况下,需要高度怀疑并进行细致的诊断检查。有淋巴结转移的典型类癌完全切除后预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d1/7930577/7a7cfd802cad/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d1/7930577/f78ffffbc152/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d1/7930577/12025de3c304/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d1/7930577/f85eb4ce626b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d1/7930577/7a7cfd802cad/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d1/7930577/f78ffffbc152/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d1/7930577/12025de3c304/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d1/7930577/f85eb4ce626b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d1/7930577/7a7cfd802cad/gr4.jpg

相似文献

1
Bronchial carcinoid tumor in the era of covid-19 pandemic: A case report.新冠疫情时代的支气管类癌肿瘤:一例报告
Int J Surg Case Rep. 2021 Mar;80:105703. doi: 10.1016/j.ijscr.2021.105703. Epub 2021 Feb 24.
2
Bronchial carcinoid tumor: A case report.支气管类癌肿瘤:一例报告。
Int J Surg Case Rep. 2020;77:349-352. doi: 10.1016/j.ijscr.2020.11.043. Epub 2020 Nov 11.
3
Bronchial carcinoid misdiagnosed as COVID pneumonia: a case report.支气管类癌误诊为新冠肺炎:一例报告
Ann Med Surg (Lond). 2023 Apr 13;85(5):2194-2197. doi: 10.1097/MS9.0000000000000653. eCollection 2023 May.
4
Bronchial carcinoid: a neuroendocrine manifestation-presented as bronchospasm and hypertension during resection.支气管类癌:一种神经内分泌表现——在切除术中表现为支气管痉挛和高血压。
Indian J Thorac Cardiovasc Surg. 2024 Sep;40(5):603-607. doi: 10.1007/s12055-024-01689-7. Epub 2024 Jan 27.
5
[Bronchopulmonary carcinoid tumours].[支气管肺类癌肿瘤]
Minerva Chir. 2002 Aug;57(4):403-23.
6
[The ectopic ACTH syndrome].[异位促肾上腺皮质激素综合征]
Srp Arh Celok Lek. 2004 Jan-Feb;132(1-2):28-32. doi: 10.2298/sarh0402028p.
7
[Pulmonary carcinoid tumors].[肺类癌肿瘤]
Radiologe. 2017 May;57(5):397-406. doi: 10.1007/s00117-017-0243-x.
8
[A case of recurrent cough in bronchial carcinoid].[一例支气管类癌复发性咳嗽病例]
Pediatr Med Chir. 1999 Mar-Apr;21(2):93-5.
9
Primary bronchial carcinoid: A rare differential diagnosis of pulmonary koch in young adult patient.原发性支气管类癌:年轻成年患者肺部结核的一种罕见鉴别诊断。
Lung India. 2012 Jan;29(1):59-62. doi: 10.4103/0970-2113.92366.
10
[Pulmonary carcinoid: analysis of a single institutional experience and prognostic factors].[肺类癌:单机构经验及预后因素分析]
Acta Med Port. 2014 Nov-Dec;27(6):749-54. Epub 2014 Dec 30.

引用本文的文献

1
Bronchial carcinoid misdiagnosed as COVID pneumonia: a case report.支气管类癌误诊为新冠肺炎:一例报告
Ann Med Surg (Lond). 2023 Apr 13;85(5):2194-2197. doi: 10.1097/MS9.0000000000000653. eCollection 2023 May.
2
Coronavirus disease 2019 in patients with neuroendocrine neoplasms: Preliminary results of the INTENSIVE study.2019 年冠状病毒病患者的神经内分泌肿瘤:INTENSIVE 研究的初步结果。
Eur J Cancer. 2021 Sep;154:246-252. doi: 10.1016/j.ejca.2021.06.029. Epub 2021 Jun 30.

本文引用的文献

1
The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines.SCARE 2020 指南:更新共识手术病例报告(SCARE)指南。
Int J Surg. 2020 Dec;84:226-230. doi: 10.1016/j.ijsu.2020.10.034. Epub 2020 Nov 9.
2
False-positive COVID-19 results: hidden problems and costs.新冠病毒检测假阳性结果:潜在问题与成本
Lancet Respir Med. 2020 Dec;8(12):1167-1168. doi: 10.1016/S2213-2600(20)30453-7. Epub 2020 Sep 29.
3
Lung Cancer and the COVID-19 pandemic: Recommendations from the Brazilian Thoracic Oncology Group.
肺癌与 COVID-19 大流行:巴西胸肿瘤学组的建议。
Clinics (Sao Paulo). 2020 Jun 22;75:e2060. doi: 10.6061/clinics/2020/e2060. eCollection 2020.
4
Introduction to The 2015 World Health Organization Classification of Tumors of the Lung, Pleura, Thymus, and Heart.《2015年世界卫生组织肺、胸膜、胸腺和心脏肿瘤分类》简介
J Thorac Oncol. 2015 Sep;10(9):1240-1242. doi: 10.1097/JTO.0000000000000663.
5
Parenchyma-sparing bronchial sleeve resections in trauma, benign and malign diseases.在创伤、良性和恶性疾病中保留实质的支气管袖状切除术。
Thorac Cardiovasc Surg. 2010 Feb;58(1):32-7. doi: 10.1055/s-0029-1186241. Epub 2010 Jan 13.
6
Proceedings of the IASLC International Workshop on Advances in Pulmonary Neuroendocrine Tumors 2007.2007年国际肺癌研究协会肺神经内分泌肿瘤进展国际研讨会会议记录
J Thorac Oncol. 2008 Oct;3(10):1194-201. doi: 10.1097/JTO.0b013e3181861d7b.
7
Neuroendocrine tumors of the lung: clinical, pathologic, and imaging findings.肺神经内分泌肿瘤:临床、病理及影像学表现
Radiographics. 2006 Jan-Feb;26(1):41-57; discussion 57-8. doi: 10.1148/rg.261055057.
8
The spectrum of carcinoid tumours and carcinoid syndromes.类癌肿瘤和类癌综合征的谱系
Ann Clin Biochem. 2003 Nov;40(Pt 6):612-27. doi: 10.1258/000456303770367207.
9
Bronchial carcinoid tumors of the thorax: spectrum of radiologic findings.胸部支气管类癌肿瘤:放射学表现谱
Radiographics. 2002 Mar-Apr;22(2):351-65. doi: 10.1148/radiographics.22.2.g02mr01351.
10
Treatment and prognosis in bronchial carcinoids involving regional lymph nodes.累及区域淋巴结的支气管类癌的治疗与预后
J Thorac Cardiovasc Surg. 1994 Jan;107(1):1-6; discussion 6-7.