Mindaye Esubalew Taddese, Kassahun Mulugeta, Tigiye Gulilat
Department of Surgery, Saint Paul's Hospital Millennium Medical College, Swaziland Street, 1271, Addis Ababa, Ethiopia.
Department of Surgery, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Int J Surg Case Rep. 2021 Mar;80:105703. doi: 10.1016/j.ijscr.2021.105703. Epub 2021 Feb 24.
Bronchial carcinoid tumors are rare, slow growing, malignant neuroendocrine tumors which arise from Enterochromaffin (Kulchitsky) cells. Early diagnosis is extremely important as the main stay of treatment is surgical excision.
We present a rare case of bronchial typical carcinoid tumor in a 27-year-old male who presented with a complaint of intermittent dry cough of 2 weeks' duration associated with shortness of breath and low grade fever. He was initially misdiagnosed as covid-19 pneumonia and was admitted to covid-19 treatment center. Right lung bi-lobectomy with regional lymph node resection was done and he was discharged home in good condition.
Majority of typical carcinoids are located in the central airways leading to bronchial obstruction with recurrent pneumonia, chest pain and wheezing. In the era of covid-19 pandemic, lung cancer patients are at higher risk of being affected by covid-19 and, early identification and differential diagnosis is extremely difficult in the absence of comprehensive evaluation and work up as the clinical and imaging findings of covid-19 may resemble lung cancer. Although hilar and mediastinal lymph nodes are the most common metastatic sites for typical carcinoids most lymphadenopathies are caused by a reactive inflammatory reaction.
Bronchial carcinoids are rare, malignant neuroendocrine tumors with complete surgical resection being the only curative management. During the Covid-19 pandemic crisis, diagnosing rare lung diseases like carcinoid tumor is real challenge especially in resource limited set up and needs high index of suspicion with meticulous diagnostic work up. The outcome of typical carcinoids with lymph node metastasis is excellent with complete resection.
支气管类癌是罕见的、生长缓慢的恶性神经内分泌肿瘤,起源于嗜银(库尔契茨基)细胞。由于主要治疗方法是手术切除,早期诊断极为重要。
我们报告一例罕见的支气管典型类癌病例,患者为一名27岁男性,主诉持续2周的间歇性干咳,伴有呼吸急促和低热。他最初被误诊为新冠病毒肺炎,并被收治于新冠病毒治疗中心。进行了右肺双叶切除术及区域淋巴结切除术,患者康复出院。
大多数典型类癌位于中央气道,导致支气管阻塞,出现反复肺炎、胸痛和喘息。在新冠疫情时代,肺癌患者感染新冠病毒的风险更高,在缺乏全面评估和检查的情况下,由于新冠病毒的临床和影像学表现可能与肺癌相似,早期识别和鉴别诊断极为困难。尽管肺门和纵隔淋巴结是典型类癌最常见的转移部位,但大多数淋巴结肿大是由反应性炎症引起的。
支气管类癌是罕见的恶性神经内分泌肿瘤,完整手术切除是唯一的治愈性治疗方法。在新冠疫情危机期间,诊断类癌等罕见肺部疾病是一项真正的挑战,尤其是在资源有限的情况下,需要高度怀疑并进行细致的诊断检查。有淋巴结转移的典型类癌完全切除后预后良好。