Poroshin K K, Krylov L M, Kudriavtsev B K
Arkh Patol. 1988;50(1):32-8.
The authors present clinical and morphological characteristics of gastric leiomyoblastoma (25 cases) nominated by Soviet investigators as a myoid or angioleiomyomatous variant of a glomus tumor. The tumor was composed of leiomyomatous sites, clusters of epithelioid cells with apparently empty cytoplasm and frequently odd nuclei. Morphological criteria are suggested referring leiomyoblastoma to mature, infiltrative and malignant. Electron-microscopic examination in 8 cases provided evidence for myogenic origin of the neoplasm. Smooth muscle differentiation is shown to resolve with growing of cell proliferation and relevant atypia.
作者介绍了胃平滑肌瘤(25例)的临床和形态学特征,苏联研究人员将其命名为血管球瘤的肌样或血管平滑肌瘤变体。肿瘤由平滑肌瘤部位、上皮样细胞簇组成,细胞质明显空泡化,核常怪异。提出了将平滑肌瘤分为成熟型、浸润型和恶性型的形态学标准。8例的电子显微镜检查为肿瘤的肌源性起源提供了证据。随着细胞增殖和相关异型性的增加,平滑肌分化消失。