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Inflammatory Endotype-associated Airway Microbiome in Chronic Obstructive Pulmonary Disease Clinical Stability and Exacerbations: A Multicohort Longitudinal Analysis.慢性阻塞性肺疾病临床稳定期和加重期的炎症表型相关气道微生物组：一项多队列纵向分析。
Am J Respir Crit Care Med. 2021 Jun 15;203(12):1488-1502. doi: 10.1164/rccm.202009-3448OC.
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Distinct associations of sputum and oral microbiota with atopic, immunologic, and clinical features in mild asthma.痰和口腔微生物群与轻度哮喘的特应性、免疫学和临床特征的不同关联。
J Allergy Clin Immunol. 2020 Nov;146(5):1016-1026. doi: 10.1016/j.jaci.2020.03.028. Epub 2020 Apr 13.
3
Methods in Lung Microbiome Research.肺微生物组研究方法。
Am J Respir Cell Mol Biol. 2020 Mar;62(3):283-299. doi: 10.1165/rcmb.2019-0273TR.
4
Measures of Cystic Fibrosis Airway Microbiota during Periods of Clinical Stability.囊性纤维化气道微生物组在临床稳定期的测量。
Ann Am Thorac Soc. 2019 Dec;16(12):1534-1542. doi: 10.1513/AnnalsATS.201903-270OC.
5
Inflammatory endotypes in COPD.COPD 的炎症内型。
Allergy. 2019 Jul;74(7):1249-1256. doi: 10.1111/all.13760. Epub 2019 Mar 31.
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Chronic Obstructive Pulmonary Disease Biomarkers and Their Interpretation.慢性阻塞性肺疾病生物标志物及其解读。
Am J Respir Crit Care Med. 2019 May 15;199(10):1195-1204. doi: 10.1164/rccm.201810-1860SO.
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Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials.慢性阻塞性肺疾病患者加重风险和布地奈德治疗反应的预测因素：三项随机试验的事后分析。
Lancet Respir Med. 2018 Feb;6(2):117-126. doi: 10.1016/S2213-2600(18)30006-7. Epub 2018 Jan 10.
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Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort.痰和血嗜酸性粒细胞浓度与 COPD 严重程度的临床指标的关联：SPIROMICS 队列分析。
Lancet Respir Med. 2017 Dec;5(12):956-967. doi: 10.1016/S2213-2600(17)30432-0. Epub 2017 Nov 13.
9
Airway Mucin Concentration as a Marker of Chronic Bronchitis.气道黏液浓度作为慢性支气管炎的一个标志物
N Engl J Med. 2017 Sep 7;377(10):911-922. doi: 10.1056/NEJMoa1701632.
10
Do COPD subtypes really exist? COPD heterogeneity and clustering in 10 independent cohorts.慢性阻塞性肺疾病（COPD）亚型真的存在吗？10个独立队列中的COPD异质性与聚类分析
Thorax. 2017 Nov;72(11):998-1006. doi: 10.1136/thoraxjnl-2016-209846. Epub 2017 Jun 21.

Crossing Kingdoms: Host-Microbial Endotyping and the Quest to Understand Treatable Traits in Chronic Obstructive Pulmonary Disease.

作者信息

Segal Leopoldo N, Huang Yvonne J

机构信息

Division of Pulmonary, Critical Care, and Sleep Medicine New York University School of Medicine, New York New York.

Division of Pulmonary and Critical Care Medicine University of Michigan Ann Arbor, Michigan.

出版信息

Am J Respir Crit Care Med. 2021 Jun 15;203(12):1447-1448. doi: 10.1164/rccm.202101-0169ED.

DOI:10.1164/rccm.202101-0169ED
PMID:33651664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8483227/
Abstract
摘要