Department of Palliative Medicine, Munich University Hospital, Ludwig-Maximilians-University Munich, Germany.
Department of Palliative Medicine, Munich University Hospital, Ludwig-Maximilians-University Munich, Germany.
J Pain Symptom Manage. 2021 Sep;62(3):e28-e37. doi: 10.1016/j.jpainsymman.2021.02.033. Epub 2021 Feb 27.
Drug therapy is an integral part of palliative care but pharmacotherapy can be challenging for health care professionals. Access to information is essential for health care providers to choose the best drug treatment for an individual patient. A drug information service can support health care professionals to obtain appropriate, unbiased information.
To describe the enquiries to a palliative care drug information service. Objectives are to determine the information needs (including off-label use) of different professional groups and areas of care, to identify subject areas and drug substances for which there is a high need for information.
Retrospective evaluation of all enquiries to a palliative care drug information service within 24 months from July 2017 to June 2019.
During the study period, 477 enquiries reached the drug information service, mostly from physicians (59%), followed by pharmacists (31%). Ketamin was the most discussed drug (11%), in general enquiries or corresponding replies mostly contained drugs targeting the nervous system, such as analgesics. Application techniques (26%) was the most relevant category, cancer pain (24%) was the most frequently addressed symptom. About half of the enquiries (48%) dealt with off-label us, regarding an application mode outside the license.
The information needs on palliative care pharmacotherapy seem to be particularly high among physicians. The demand for information in the area of application technology is particularly apparent and demonstrates a therapeutic gap in terms of availability of suitable preparations as well as necessary information.
药物治疗是姑息治疗的一个组成部分，但药物治疗对医疗保健专业人员来说可能具有挑战性。获取信息对于医疗保健提供者为个体患者选择最佳药物治疗至关重要。药物信息服务可以支持医疗保健专业人员获取适当、无偏见的信息。
描述姑息治疗药物信息服务的咨询情况。目的是确定不同专业群体和护理领域的信息需求（包括标签外使用），确定需要大量信息的主题领域和药物物质。
对 2017 年 7 月至 2019 年 6 月的 24 个月内向姑息治疗药物信息服务提出的所有咨询进行回顾性评估。
在研究期间，477 条咨询信息到达药物信息服务，主要来自医生（59%），其次是药剂师（31%）。氯胺酮是讨论最多的药物（11%），一般咨询或相应回复主要包含针对神经系统的药物，如镇痛药。应用技术（26%）是最相关的类别，癌症疼痛（24%）是最常涉及的症状。约一半的咨询（48%）涉及标签外使用，即许可证规定的应用模式之外的使用。
姑息治疗药物治疗的信息需求似乎在医生中特别高。对应用技术领域信息的需求尤其明显，表明在可用性合适制剂和必要信息方面存在治疗差距。
