State Key Laboratory of Animal Nutrition, Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
State Key Laboratory of Animal Nutrition, Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Poult Sci. 2021 Mar;100(3):100945. doi: 10.1016/j.psj.2020.12.042. Epub 2020 Dec 25.
Polyphasic myodegeneration potentially causes severe physiological and metabolic disorders in the breast muscle of fast-growing broiler chickens. To date, the etiology of recent muscle myopathies, such as the white striping (WS) phenotype, is still unknown. White striping-affected breast meats compromise the water holding capacity and predispose muscle to poor vascular tone, leading to the deterioration of meat qualities. Herein, this review article provides insight on the complexities around chicken breast myopathies: (i) the etiologies of WS occurrence in chicken; (ii) the metabolic changes that occur in WS defect in pectoralis major; and (iii) the interactions between breast muscle physiology and vascular tone. It also addressed the effects of nutritional supplements on muscle myopathies on chicken breast meats. Moreover, the review explored breast muscle biology focusing on the early preparation of satellite and vascular cells in fast-growth chicken breeds. Transcriptomics and histological analyses revealed poor vascularity in breast muscle of fast growth chickens. Thus, we suggest in ovo feeding of nutrients promoting vascularization and satellite cells replenishment as a potential strategy to enhance endothelium-derived nitric oxide availability to promote vascularization in the pectoralis major muscle region.
多相肌退变可能导致快速生长肉鸡的胸肌发生严重的生理和代谢紊乱。迄今为止，最近发生的一些肌肉肌病（如白条（WS）表型）的病因仍不清楚。受白条影响的胸肉会降低保水能力，并使肌肉容易出现血管张力不良，从而导致肉质恶化。本文综述了有关鸡胸脯肌肌病的复杂性：（i）鸡发生 WS 的病因；（ii）胸肌大肌 WS 缺陷中发生的代谢变化；以及（iii）胸肌生理学和血管张力之间的相互作用。还讨论了营养补充剂对鸡胸肉肌病的影响。此外，该综述还探讨了胸肌生物学，重点研究了快速生长鸡种中卫星细胞和血管细胞的早期准备。转录组学和组织学分析显示，快速生长鸡的胸肌血管生成不良。因此，我们建议在胚胎期喂养促进血管生成和卫星细胞补充的营养物质，作为提高胸肌大肌区域内皮衍生一氧化氮可用性以促进血管生成的潜在策略。
