Anti-EGFR Antibody Plus Chemotherapy Treatment in a Patient with Synchronous Merkel Cell Carcinoma and Colorectal Cancer.
作者信息
Custodio-Cabello Sara, Cabezón-Gutiérrez Luis, Palka-Kotlowska Magda, Oliveros Acebes Eduardo, Khosravi-Shahi Parham
机构信息
Medical Oncology, Hospital Universitario de Torrejón, Madrid, ESP.
Internal Medicine, Hospital Universitario de Torrejón, Madrid, ESP.
出版信息
Cureus. 2021 Jan 26;13(1):e12916. doi: 10.7759/cureus.12916.
Abstract
Merkel cell carcinoma (MCC) is a rare neuroendocrine cutaneous malignancy. During early stages, surgery is the primary treatment followed by radiotherapy in patients at high risk of recurrence. Definitive radiation therapy is an alternative for patients who are not surgical candidates, reserving chemotherapy for metastatic disease. We present a case of a male patient diagnosed with MCC and stage IV colorectal cancer and we focus on the skin tumor shrinkage after specific colorectal cancer treatment.
摘要
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本文引用的文献
1
Durable Tumor Regression and Overall Survival in Patients With Advanced Merkel Cell Carcinoma Receiving Pembrolizumab as First-Line Therapy.
J Clin Oncol. 2019 Mar 20;37(9):693-702. doi: 10.1200/JCO.18.01896. Epub 2019 Feb 6.
2
The association between geographic location and incidence of Merkel cell carcinoma in comparison to melanoma: An international assessment.
Eur J Cancer. 2018 May;94:47-60. doi: 10.1016/j.ejca.2018.02.003. Epub 2018 Mar 20.
3
Merkel cell carcinoma incidence is increasing in Sweden.
J Eur Acad Dermatol Venereol. 2016 Oct;30(10):1708-1713. doi: 10.1111/jdv.13698. Epub 2016 May 2.
4
Skin Cancer Incidence and Mortality in Spain: A Systematic Review and Meta-Analysis.
Actas Dermosifiliogr. 2016 May;107(4):318-28. doi: 10.1016/j.ad.2015.12.008. Epub 2016 Feb 4.
5
Diagnosis and treatment of Merkel Cell Carcinoma. European consensus-based interdisciplinary guideline.
Eur J Cancer. 2015 Nov;51(16):2396-403. doi: 10.1016/j.ejca.2015.06.131. Epub 2015 Aug 6.
6
Merkel Cell Carcinoma: Epidemiology, Target, and Therapy.
Curr Dermatol Rep. 2014 Jan 22;3(1):46-53. doi: 10.1007/s13671-014-0068-z. eCollection 2014.
7
Merkel cell carcinoma demographics, morphology, and survival based on 3870 cases: a population based study.
J Cutan Pathol. 2010 Jan;37(1):20-7. doi: 10.1111/j.1600-0560.2009.01370.x. Epub 2009 Jul 23.
8
Expression of VEGF-A/C, VEGF-R2, PDGF-alpha/beta, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma.
Mod Pathol. 2008 Jul;21(7):876-84. doi: 10.1038/modpathol.2008.63. Epub 2008 Apr 11.
9
Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features.
J Am Acad Dermatol. 2008 Mar;58(3):375-81. doi: 10.1016/j.jaad.2007.11.020.
10
Merkel cell carcinoma and multiple primary cancers.
Cancer Epidemiol Biomarkers Prev. 2006 Aug;15(8):1545-9. doi: 10.1158/1055-9965.EPI-05-0895.
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