Krebs Nathan M, VanWagner Michael J, Marchewka Tiffany, Faraj Usama, Vitale Christopher R
McLaren Macomb Orthopedic Surgery Resident, Michigan State University Statewide Campus System.
Michigan State University College of Osteopathic Medicine Medical Student.
Spartan Med Res J. 2019 Mar 4;3(3):7026. doi: 10.51894/001c.7026.
Although regularly used as a method to reduce blood loss in elective orthopedic procedures (e.g., total hip and knee arthroplasty), there currently is little evidence concerning the optimal dosage, timing and route for the use of tranexamic acid to reduce postoperative blood loss in hip fracture repair.
The current literature suggests that tranexamic acid may be used to reduce postoperative blood loss in addition to reducing the risk of requiring blood transfusions following the surgical repair of hip fractures. Furthermore, it may have the potential to improve patient outcomes and decrease the overall costs of caring for this patient population.
Further studies are needed to truly gauge the effect of tranexamic acid on long-term patient outcomes and hospital costs.
尽管氨甲环酸在择期骨科手术（如全髋关节和膝关节置换术）中常被用作减少失血的方法，但目前关于其在髋部骨折修复中减少术后失血的最佳剂量、给药时间和途径的证据很少。
当前文献表明，氨甲环酸除了可降低髋部骨折手术修复后输血的风险外，还可用于减少术后失血。此外，它可能有改善患者预后并降低护理该患者群体总体成本的潜力。
需要进一步研究以真正评估氨甲环酸对患者长期预后和医院成本的影响。
