Zapata P, Torrealba G
Laboratory of Neurobiology, Catholic University of Chile, Santiago.
Brain Res. 1988 Mar 29;445(1):19-29. doi: 10.1016/0006-8993(88)91069-4.
In pentobarbitone-anesthetized cats, electrical stimulation of the central ends of the main trunks of transected hypoglossal nerves evoked vascular (pressor or depressor) reactions, mydriasis, slow and deep breathing, and reflex activation of laryngeal and facial muscles. Stimulation of the central end of the transected ramus descendens hypoglossi also provoked reflex contraction of cricothyroideus. These reflexes may be elicited also after intracranial section of hypoglossal nerve roots, but not after intracranial section of ipsilateral vagal roots. The above reflexes were abolished by acute section of the ipsilateral hypoglossonodosal branch, but they may be reproduced by electrical stimulation of the central end of this anastomotic branch between hypoglossal nerve and nodose ganglion. Stimulation of the central end of one transected hypoglossus evoked reflex efferent discharges in contralateral hypoglossus and contraction of contralateral tongue muscles. Stimulation of the central end of one transected hypoglossal end-branch inhibited efferent discharges in another end-branch. The crossed hypoglossohypoglossal reflex and the ipsilateral reflex inhibition were abolished by section of the hypoglossonodosal branch or vagal roots at the stimulated side. We conclude that reflexes evoked by stimulation of peripheral hypoglossal nerve in cats are mediated by afferent fibers directed to the nodose ganglion and entering the brain stem via vagal roots.
在戊巴比妥麻醉的猫中，电刺激横断舌下神经主要干的中枢端可诱发血管（升压或降压）反应、瞳孔散大、呼吸缓慢且深沉，以及喉和面部肌肉的反射性激活。刺激横断的舌下神经降支的中枢端也可引起环甲肌的反射性收缩。这些反射在舌下神经根颅内切断后也可引出，但在同侧迷走神经根颅内切断后则不能引出。上述反射可通过急性切断同侧舌下神经节支而消除，但通过电刺激舌下神经与结状神经节之间的这条吻合支的中枢端又可再现。刺激一侧横断的舌下神经中枢端可在对侧舌下神经诱发反射性传出放电，并使对侧舌肌收缩。刺激一侧横断的舌下神经终支中枢端可抑制另一侧终支的传出放电。刺激侧的舌下神经节支或迷走神经根切断后，交叉性舌下神经反射和同侧反射抑制均消失。我们得出结论，猫中刺激外周舌下神经诱发的反射是由传入纤维介导的，这些传入纤维指向结状神经节并通过迷走神经根进入脑干。
