Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education of China, Beijing, PR China.
Medicine (Baltimore). 2021 Mar 5;100(9):e24772. doi: 10.1097/MD.0000000000024772.
To explore the association of chronic rhinosinusitis (CRS) with bronchial asthma (BA) as well as its severity.
A comprehensive database search will be performed from PubMed, Embase, Cochrane Library, and Web of science for related literatures. Heterogeneity test will be used to assess each outcome indicator. If heterogeneity statistics I2 ≥ 50%, the random effects model will be applied; if I2 < 50%, the fixed effects model will be performed. Sensitivity analysis will be performed in all models. STATA 15.0 software (Stata Corporation, College Station, TX) will be used for statistical analysis. Risk ratio (RR) will be used as the effect size for enumeration data. P < .05 is considered statistically significant.
This study will evaluate the association of CRS with the prevalence of BA as well as its severity.
10.17605/OSF.IO/GCTM9.
探讨慢性鼻-鼻窦炎（CRS）与支气管哮喘（BA）及其严重程度的相关性。
通过 PubMed、Embase、Cochrane 图书馆和 Web of Science 对相关文献进行全面的数据库检索。将使用异质性检验来评估每个结局指标。如果异质性统计量 I2≥50%，将应用随机效应模型；如果 I2<50%，将采用固定效应模型。所有模型均进行敏感性分析。使用 STATA 15.0 软件（Stata Corporation，College Station，TX）进行统计分析。计数数据的效应大小采用风险比（RR）表示。P<0.05 被认为具有统计学意义。
本研究将评估 CRS 与 BA 的患病率及其严重程度的相关性。
OSF 注册号：10.17605/OSF.IO/GCTM9。
