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Early detection of treatment failure and early rescue intervention in multiple myeloma: time for new approaches.

作者信息

Lahuerta Juan José, Paiva Bruno, Jiménez-Ubieto Ana, Sánchez-Pina José, Mateos María-Victoria, Bladé Joan, San-Miguel Jesús F

机构信息

Instituto de Investigación Sanitaria Hospital 12 de Octubre, Fundación PETHEMA, CIBERONC number CB16/12/00369, Madrid, Spain.

Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBERONC number CB16/12/00369, Pamplona, Spain.

出版信息

Blood Adv. 2021 Mar 9;5(5):1340-1343. doi: 10.1182/bloodadvances.2020003996.

DOI:10.1182/bloodadvances.2020003996
PMID:33656540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7948301/
Abstract
摘要

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本文引用的文献

1
Newly Diagnosed Myeloma in 2020.2020年新诊断的骨髓瘤
Am Soc Clin Oncol Educ Book. 2020 Mar;40:1-15. doi: 10.1200/EDBK_280221.
2
Newly diagnosed multiple myeloma: current treatment strategies, emerging therapeutic approaches and beyond.初诊多发性骨髓瘤：当前的治疗策略、新出现的治疗方法及未来方向。
Expert Rev Hematol. 2020 Jun;13(6):669-686. doi: 10.1080/17474086.2020.1756258. Epub 2020 Apr 27.
3
OCEAN: a randomized Phase III study of melflufen + dexamethasone to treat relapsed refractory multiple myeloma.OCEAN 研究：美法仑+地塞米松治疗复发/难治性多发性骨髓瘤的随机 III 期研究。
Future Oncol. 2020 Apr;16(11):631-641. doi: 10.2217/fon-2020-0024. Epub 2020 Mar 6.
4
Multiple Myeloma: Available Therapies and Causes of Drug Resistance.多发性骨髓瘤：现有治疗方法及耐药原因
Cancers (Basel). 2020 Feb 10;12(2):407. doi: 10.3390/cancers12020407.
5
Measurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma.基于新一代流式细胞术的多发性骨髓瘤微小残留病灶检测。
J Clin Oncol. 2020 Mar 10;38(8):784-792. doi: 10.1200/JCO.19.01231. Epub 2019 Nov 26.
6
Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): a randomised, multicentre, open-label, phase 3 study.依沙佐米联合泊马度胺和低剂量地塞米松与泊马度胺和低剂量地塞米松治疗复发/难治性多发性骨髓瘤患者（ICARIA-MM）：一项随机、多中心、开放性、3 期研究。
Lancet. 2019 Dec 7;394(10214):2096-2107. doi: 10.1016/S0140-6736(19)32556-5. Epub 2019 Nov 14.
7
Response-adapted intensification with cyclophosphamide, bortezomib, and dexamethasone versus no intensification in patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre, open-label, randomised, phase 3 trial.环磷酰胺、硼替佐米与地塞米松适应性强化治疗对比未强化治疗用于新诊断的多发性骨髓瘤患者（骨髓瘤XI）：一项多中心、开放标签、随机、3期试验
Lancet Haematol. 2019 Dec;6(12):e616-e629. doi: 10.1016/S2352-3026(19)30167-X. Epub 2019 Oct 14.
8
Pomalidomide, bortezomib, and dexamethasone for patients with relapsed or refractory multiple myeloma previously treated with lenalidomide (OPTIMISMM): a randomised, open-label, phase 3 trial.来那度胺治疗后复发或难治性多发性骨髓瘤患者的泊马度胺、硼替佐米和地塞米松治疗（OPTIMISMM）：一项随机、开放标签、3 期试验。
Lancet Oncol. 2019 Jun;20(6):781-794. doi: 10.1016/S1470-2045(19)30152-4. Epub 2019 May 13.
9
Relapse after complete response in newly diagnosed multiple myeloma: implications of duration of response and patterns of relapse.新诊断多发性骨髓瘤完全缓解后的复发：缓解持续时间和复发模式的意义。
Leukemia. 2019 Mar;33(3):730-738. doi: 10.1038/s41375-018-0271-1. Epub 2018 Oct 15.
10
Once weekly versus twice weekly carfilzomib dosing in patients with relapsed and refractory multiple myeloma (A.R.R.O.W.): interim analysis results of a randomised, phase 3 study.每周一次与每周两次卡非佐米给药治疗复发和难治性多发性骨髓瘤患者（A.R.R.O.W.）：一项随机、3 期研究的中期分析结果。
Lancet Oncol. 2018 Jul;19(7):953-964. doi: 10.1016/S1470-2045(18)30354-1. Epub 2018 Jun 1.