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60 岁以上患者经导管装置闭合房间隔缺损的中期预后:单中心经验。

Midterm Prognosis of Sexagenary Patients after Transcatheter Device Closure of Atrial Septal Defects: a Single-Chinese Center Experience.

机构信息

Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.

Fujian Key Laboratory of Women and Children's Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, People's Republic of China.

出版信息

Braz J Cardiovasc Surg. 2022 Mar 10;37(1):48-54. doi: 10.21470/1678-9741-2020-0387.

Abstract

INTRODUCTION

The objective of this study is to evaluate the efficacy and midterm prognosis of transcatheter device closure of atrial septal defects (ASDs) in sexagenary patients in China.

METHODS

Forty-six sexagenary patients who underwent transcatheter device closure of ASDs in our hospital were included in this study. The patients' preoperative and postoperative clinical symptoms, echocardiographic results, and quality of life were investigated and analyzed.

RESULTS

Of the 46 sexagenary patients who participated in the study, 40 completed the study. After ASD closure, the clinical symptoms of the patients significantly improved, and the number of patients with dyspnea and palpitations significantly decreased after the operation. According to the echocardiographic results, few patients had a tiny residual shunt after closure, but the shunt disappeared completely at the three-month follow-up. The size of the right ventricular cavity was significantly smaller postoperatively compared with preoperatively. Regarding the patients' quality of life, their feedback in all dimensions of the 36-Item Short-Form Health Survey (or SF-36) was significantly improved at the three-month follow-up, and it remained improved at the one-year follow-up.

CONCLUSION

The clinical outcomes and subjective quality of life of sexagenary patients with ASDs improved significantly after transcatheter device closure of ASDs. Therefore, we believe that for sexagenary patients with ASDs, transcatheter device closure is a favorable treatment.

摘要

简介

本研究旨在评估中国 60 岁以上患者经导管装置关闭房间隔缺损(ASD)的疗效和中期预后。

方法

本研究纳入了 46 例在我院接受经导管装置关闭 ASD 的 60 岁以上患者。对患者术前和术后的临床症状、超声心动图结果和生活质量进行了调查和分析。

结果

在参与研究的 46 例 60 岁以上患者中,有 40 例完成了研究。ASD 关闭后,患者的临床症状明显改善,呼吸困难和心悸的患者数量在手术后明显减少。根据超声心动图结果,少数患者在关闭后存在微小残余分流,但在三个月随访时完全消失。与术前相比,术后右心室腔明显缩小。关于患者的生活质量,他们在 36 项简短健康调查问卷(或 SF-36)所有维度的反馈在三个月随访时均显著改善,且在一年随访时仍在改善。

结论

经导管装置关闭 ASD 后,60 岁以上 ASD 患者的临床结局和主观生活质量显著改善。因此,我们认为对于 60 岁以上的 ASD 患者,经导管装置关闭是一种有利的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34b1/8973138/75dd60b57d8d/rbccv-37-01-0048-g01.jpg

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