经导管封堵房间隔缺损和卵圆孔未闭封堵器的最新进展。
Recent development of transcatheter closure of atrial septal defect and patent foramen ovale with occluders.
机构信息
College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, 266042, People's Republic of China.
Qingdao Children's Heart Center, Qingdao Women and Children's Hospital, Congenital Heart Dieases Research Center of Qingdao University, Qingdao, 266034, People's Republic of China.
出版信息
J Biomed Mater Res B Appl Biomater. 2018 Jan;106(1):433-443. doi: 10.1002/jbm.b.33831. Epub 2016 Dec 26.
Atrial septal defect (ASD) and patent foramen ovale (PFO) are common clinical congenital heart defects. As an effective method for the treatment of ASD and PFO, transcatheter closure with occluders presents many advantages, including safety, ease of operation, minimal invasiveness, and reduced complications. This contribution reviews the various types of occluders currently used in clinical applications and under development, including non degradable occluders, partially degradable occluders, and totally degradable occluders. A number of case studies are described in detail. Comparison is made on the treatment outcomes using different occulders. Future development of transcatheter closure is discussed, in particular the use of totally degradable occluders. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 433-443, 2018.
房间隔缺损（ASD）和卵圆孔未闭（PFO）是常见的临床先天性心脏缺陷。作为 ASD 和 PFO 的有效治疗方法，封堵器经导管封堵具有安全性高、操作简便、微创和减少并发症等优点。本文综述了目前临床应用和正在开发的各种类型的封堵器，包括不可降解封堵器、部分降解封堵器和完全降解封堵器。详细描述了一些案例研究。比较了不同封堵器的治疗效果。讨论了经导管封堵的未来发展，特别是完全可降解封堵器的应用。© 2016 Wiley Periodicals, Inc. J 生物材料研究杂志 B：应用生物材料，106B:433-443, 2018.
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