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黄斑脱离型孔源性视网膜脱离修复术后光学相干断层扫描血管造影对黄斑区解剖结构和功能变化的评估

Assessment of Anatomical and Functional Macular Changes with Optical Coherence Tomography Angiography After Macula-Off Rhegmatogenous Retinal Detachment Repair.

作者信息

Christou Evita Evangelia, Kalogeropoulos Christos, Georgalas Ilias, Stavrakas Panagiotis, Christodoulou Eleni, Batsos Georgios, Stefaniotou Maria

机构信息

Department of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.

First Department of Ophthalmology, General Hospital of Athens G. Gennimatas, Medical School, National and Kapodistrian University of Athens, Greece.

出版信息

Semin Ophthalmol. 2021 Apr 3;36(3):119-127. doi: 10.1080/08820538.2021.1889618. Epub 2021 Mar 3.

Abstract

To evaluate macular capillary plexus changes with OCT-angiography with regard to macular detachment duration in macula-off rhegmatogenous retinal detachment (RRD).: 23 eyes of 23 patients were included in this retrospective case-control study and were divided into 2 groups. Group-A had a macular detachment duration of 0 to 10 days and group-B of 11 to 30 days. All eyes underwent a single successful pars plana vitrectomy (PPV) and gas tamponade. We analysed the OCT-A characteristics and visual outcomes at 12 weeks postoperatively in the 2 groups. The fellow eye was used as control. Vessel density (VD) and flow density (FD) in the superficial capillary plexus (SCP) were significantly lower in group-B ( < .01) than in group-A and control. FAZ SCP in both groups was significantly larger than the control ( < .01), although it did not differ significantly between the two groups ( = 1.000). BCVA was significantly lower in group-B compared to group-A ( < .01). BCVA was positively correlated with VD SCP in group B ( = .015), but not in group-A. Postoperative BCVA had no correlation with FAZ SCP in both groups. The macular detachment duration could be a predicting factor of flow density in macular capillary plexus which in turn might be an indicator of visual outcomes in chronic cases.

摘要

目的

通过光学相干断层扫描血管造影(OCTA)评估黄斑裂孔性视网膜脱离(RRD)黄斑脱离持续时间与黄斑毛细血管丛变化之间的关系。方法:本回顾性病例对照研究纳入23例患者的23只眼,分为两组。A组黄斑脱离持续时间为0至10天,B组为11至30天。所有患眼均接受了一次成功的玻璃体切割术(PPV)联合气体填充。我们分析了两组术后12周时的OCTA特征和视力结果。对侧眼作为对照。B组浅表毛细血管丛(SCP)的血管密度(VD)和血流密度(FD)显著低于A组和对照组(P<0.01)。两组SCP的黄斑无血管区(FAZ)均显著大于对照组(P<0.01),但两组之间无显著差异(P = 1.000)。B组的最佳矫正视力(BCVA)显著低于A组(P<0.01)。B组BCVA与SCP的VD呈正相关(P = 0.015),而A组则无相关性。两组术后BCVA与SCP的FAZ均无相关性。黄斑脱离持续时间可能是黄斑毛细血管丛血流密度的预测因素,进而可能是慢性病例视力结果的一个指标。

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