一种蛋白酶抑制剂对大肠杆菌蛋白质生物合成的影响。
Effects of a protease inhibitor on biosynthesis of Escherichia coli proteins.
作者信息
Ito K
出版信息
J Bacteriol. 1977 Dec;132(3):1021-3. doi: 10.1128/jb.132.3.1021-1023.1977.
Abstract
A protease inhibitor, tosyl-L-lysine chloromethylketone, altered the composition of newly synthesized protein in Escherichia coli; a significant portion of the proteins synthesized sedimented rapidly, presumably forming aggregates of the abnormal proteins. Protein I of the outer membrane was only slightly synthesized under these conditions.
摘要
一种蛋白酶抑制剂，甲苯磺酰-L-赖氨酸氯甲基酮，改变了大肠杆菌中新合成蛋白质的组成；相当一部分合成的蛋白质迅速沉降，推测形成了异常蛋白质的聚集体。在这些条件下，外膜的蛋白质I仅少量合成。
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