焦虑障碍与帕金森病的关系：临床与治疗问题。
The Relationship Between Anxiety Disorders and Parkinson's Disease: Clinical and Therapeutic Issues.
机构信息
Faculty of Medical Sciences, Psychiatry Department, Lebanese University, Beirut, Lebanon.
Psychiatry Department, Mount Lebanon Hospital, P.O. Box 470, Blvd. Camille Chamoun, Hazmieh, Beirut, Lebanon.
出版信息
Curr Psychiatry Rep. 2021 Mar 3;23(4):20. doi: 10.1007/s11920-021-01229-9.
PURPOSE OF REVIEW
This paper seeks to describe anxiety's different symptomatologic presentations in Parkinson's disease (PD), its longitudinal course and predictors, as well as its motor and non-motor correlates. It also reviews the available screening tools and different treatment modalities.
RECENT FINDINGS
In PD, longitudinal predictors of anxiety are mostly non-motor non-dopaminergic symptoms. The longitudinal course of anxiety is mainly a stable one. The Parkinson Anxiety Scale and the Geriatric Anxiety Scale are the 2 recommended screening tools. A third of PD patients suffer from an anxiety disorder at any time point. It can precede or follow PD motor symptoms. Anxiety is associated with demographic, disease-related motor and non-motor features. There is a lack of studies evaluating psychotropic treatment of anxiety in PD. Adjustment of dopaminergic treatment is indicated when anxiety is associated with motor fluctuations. DBS can be useful as well as CBT and body-mind interventions.
目的综述
本文旨在描述帕金森病（PD）中焦虑的不同症状表现、纵向病程及其预测因素，以及与运动和非运动相关的症状。还回顾了现有的筛查工具和不同的治疗方式。
最近的发现
在 PD 中，焦虑的纵向预测因素主要是非运动非多巴胺能症状。焦虑的纵向病程主要是稳定的。帕金森焦虑量表和老年焦虑量表是 2 种推荐的筛查工具。三分之一的 PD 患者在任何时间点都患有焦虑症。它可以先于或后于 PD 的运动症状。焦虑与人口统计学、疾病相关的运动和非运动特征有关。目前还缺乏评估 PD 焦虑症的精神药物治疗的研究。当焦虑与运动波动相关时，应调整多巴胺能治疗。DBS 以及 CBT 和身心干预都可能有用。
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