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结直肠手术中血栓栓塞性疾病预防性管理的失败。

Failure in prophylactic management of thromboembolic disease in colorectal surgery.

作者信息

Wille-Jørgensen P, Kjaergaard J, Jørgensen T, Korsgaard Larsen T

机构信息

Department of Surgical Gastroenterology, Herlev Hospital, University of Copenhagen, Denmark.

出版信息

Dis Colon Rectum. 1988 May;31(5):384-6. doi: 10.1007/BF02564891.

Abstract

The operative courses of 294 elective consecutive colorectal resections were reviewed in order to evaluate the morbidity and mortality of postoperative thromboembolic complications. All patients received low-dose heparin prophylaxis. Fifty-seven patients were screened for deep venous thrombosis with the fibrinogen uptake test, and treatment of thromboembolism was started if the diagnosis was established by venography and/or pulmonary scintigraphy. Neither the morbidity nor mortality from clinical thromboembolic complications was lowered in the group of patients who were screened. Rectal surgery seems to carry a higher risk of postoperative thromboembolic complications than colon surgery, and thromboembolic complications are responsible for about half of the postoperative deaths following elective colorectal surgery.

摘要

回顾了294例连续性择期结直肠切除术的手术过程,以评估术后血栓栓塞并发症的发病率和死亡率。所有患者均接受低剂量肝素预防。57例患者通过纤维蛋白原摄取试验筛查深静脉血栓形成,若经静脉造影和/或肺闪烁扫描确诊,则开始进行血栓栓塞治疗。接受筛查的患者组中,临床血栓栓塞并发症的发病率和死亡率均未降低。直肠手术术后血栓栓塞并发症的风险似乎高于结肠手术,并且血栓栓塞并发症约占择期结直肠手术后死亡病例的一半。

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