Institute of Pain Medicine, Division of Anesthesiology, Tel Aviv Sourasky Medical Center, Israel.
Sackler School of Medicine, Tel Aviv University, Tel-Aviv, Israel.
Spine (Phila Pa 1976). 2021 Oct 15;46(20):1370-1377. doi: 10.1097/BRS.0000000000004024.
Prospective clinical pilot study and cadaveric study.
The aim of this study was to evaluate the spread of an ultrasound-guided interfascial plane blocks (UGIPBs) and its potential efficacy for cervical radiculopathy.
Cervical radiculopathy is a common disorder, potentially leading to severe pain and disability. Conservative treatment with cervical epidural steroid injections (ESI) is limited by concerns regarding their safety. UGIPBs are used in cervical surgical procedures as part of the multimodal postoperative analgesia regimen however, were not described for cervical radiculopathy.
Twelve patients with acute cervical radicular pain who failed conservative treatment and were candidates for surgery were offered a cervical retrolaminar injection. A solution of 4 mL lidocaine 0.5% and 10 mg dexamethasone was injected, assisted by ultrasound guidance, at the posterior aspect of the cervical lamina corresponding to the compressed nerve root level. Additionally, a cadaver study was carried to evaluate the contrast spread and infiltration into near structures, both anatomically and radiographically.
Twelve patients underwent the procedure, with a mean follow-up time of 14.5 weeks. Average numerical rating scale improved from 7.25 at baseline to 2.83 following the injection (P < 0.001). Three patients received 2 to 3 injections without significant improvement and were eventually operated. No adverse events were reported.In the cadaver study, fluoroscopy demonstrated contrast spread between T1 and T3 caudally, C2 to C5 cranially and facet joints laterally. Anatomically, the dye spread was demonstrated up to C2 cranially, T1 caudally, the articular pillars of C4 to C7, and the neural foramen of C6 laterally.
A solution injected into the cervical retrolaminar plane can diffuse in the cranial-caudal axis to C2-T3 and laterally to the facet joints and the cervical neural foramen. Our pilot study confirmed the feasibility of our study protocol. Future studies are needed to support our early results.Level of Evidence: 4.
前瞻性临床试点研究和尸体研究。
本研究旨在评估超声引导筋膜平面阻滞(UGIPBs)的扩散范围及其在颈神经根病中的潜在疗效。
颈神经根病是一种常见疾病,可能导致严重疼痛和残疾。颈椎硬膜外类固醇注射(ESI)的保守治疗受到对其安全性的担忧的限制。UGIPBs 用于颈椎手术作为多模式术后镇痛方案的一部分,但尚未用于颈神经根病。
12 例保守治疗失败且适合手术的急性颈神经根痛患者接受颈椎后路注射。在超声引导下,将 4 毫升 0.5%利多卡因和 10 毫克地塞米松溶液注射到相应受压神经根水平的颈椎椎板后表面。此外,还进行了尸体研究,以评估对比剂的扩散和渗透到邻近结构,包括解剖和影像学。
12 例患者接受了该手术,平均随访时间为 14.5 周。平均数字评分量表从基线时的 7.25 分改善到注射后的 2.83 分(P < 0.001)。3 例患者接受了 2 至 3 次注射,但没有明显改善,最终接受了手术。没有报告不良事件。在尸体研究中,荧光透视显示对比剂从尾部向 T1 和 T3 扩散,从头部向 C2 至 C5 扩散,向侧面向关节突关节扩散。解剖学上,染料扩散到头部 C2,尾部 T1,C4 至 C7 的关节突,以及 C6 的侧神经孔。
注入颈椎后板平面的溶液可以在颅尾轴上扩散到 C2-T3,并向侧面扩散到关节突关节和颈神经孔。我们的试点研究证实了我们的研究方案的可行性。需要进一步的研究来支持我们的早期结果。
4 级。