Höffken G, Lode H, Dissmann T, Ludwig W D, Hunsdiek K F, Krämer A, Hampl H, Zorr B, Mielke M, Bratzke B
Medizinische Klinik und Poliklinik des Klinikum Steglitz, Freie Universität, Berlin.
Dtsch Med Wochenschr. 1988 May 13;113(19):755-62. doi: 10.1055/s-2008-1067716.
Between 1983 and 1987, a stepwise diagnostic programme was undertaken prospectively in 37 of 100 HIV-positive patients with 40 bronchopulmonary infections. It consisted chiefly of flexible bronchoscopy combined with lavage, transbronchial biopsy and/or removal of bronchial brush cells. Taking into account all examinations performed in life and at autopsy, 25 of the 37 patients had Pneumocystis carinii pneumonia (67.5%), 13 had bacterial pneumonia, six of these were mycobacterial infections (atypical mycobacteria in four), eight had neoplasms (pulmonary Kaposi's sarcoma in five, squamous-cell carcinoma in two, and Hodgkin's disease in one), and four patients had cytomegalovirus infection. Total diagnostic success of bronchoscopy was 78%; related to Pneumocystis pneumonia it was 91%.
