Fan Chao, Hou Jing, Chen Yu-Jia, Ding Kui-Ling, Zhou Qi-Lin
State Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, P.R. China.
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, P.R. China.
Org Lett. 2021 Mar 19;23(6):2074-2077. doi: 10.1021/acs.orglett.1c00234. Epub 2021 Mar 4.
A rhodium-catalyzed hydroformylation of alkynes with formic acid was developed. The method provides α,β-unsaturated aldehydes in high yield and -selectivity without the need to handle toxic CO gas.
开发了一种铑催化的炔烃与甲酸的氢甲酰化反应。该方法无需处理有毒的一氧化碳气体，即可高产率和高选择性地提供α,β-不饱和醛。
