Humoral mediator-dependent activation of the Sarcophaga lectin gene.

Sarcophaga lectin is a defence protein synthesized by the fat body and secreted into the hemolymph in response to injury of the body of third instar larvae of Sarcophaga peregrina (flesh-fly). In this paper, we demonstrate that the stimulus of body injury is first transmitted to a certain tissue present in the anterior part of the body, and from there a mediator molecule that interacts directly with fat body cells is secreted into the hemolymph. On interaction with this mediator molecule, the fat body begins to synthesize mRNA for Sarcophaga lectin.