Leonhardt A
Gynäkologisch-onkologische Klinik Bad Trissl.
Geburtshilfe Frauenheilkd. 1988 Feb;48(2):92-8. doi: 10.1055/s-2008-1035701.
From 1977 to 1986, inclusively, 2511 patients with breast cancer were analysed. The following factors were evaluated: patients attitude toward screening programs, the method of cancer detection, the relation between tumor-size and axillary nodes metastases and efficiency of the currently in Germany used screening program. 65.9% of the patients underwent regular annual preventive physical examination, 15.2% irregular and 18.9% no examination. Only 12.7% of cancers were detected through the screening program, in 85% the patients discovered their tumors. Cancers up to 0.5 cm had in 25% lymph-nodes metastases and tumors up to 1.0 cm had in 27% of cases axillary nodes metastases. Breast cancers between 1.1 cm and 2.0 cm had a bad prognosis: the axillary metastases occurred in 34%-45%. Surprisingly, there were no differences in tumor size, percentage of residual tumor and frequency of axillary lymph-nodes metastases between patients who took regularly part in preventive physical examination and those never taking part. Women who irregularly participated in the program had the most unfavourable prognosis.
在1977年至1986年(含)期间,对2511例乳腺癌患者进行了分析。评估了以下因素:患者对筛查项目的态度、癌症检测方法、肿瘤大小与腋窝淋巴结转移之间的关系以及德国目前使用的筛查项目的效率。65.9%的患者每年接受定期预防性体检,15.2%的患者不定期体检,18.9%的患者未进行体检。只有12.7%的癌症是通过筛查项目检测出来的,85%的患者是自行发现肿瘤的。直径达0.5厘米的癌症有25%发生腋窝淋巴结转移,直径达1.0厘米的肿瘤有27%发生腋窝淋巴结转移。直径在1.1厘米至2.0厘米之间的乳腺癌预后较差:腋窝转移发生率为34% - 45%。令人惊讶的是,定期参加预防性体检的患者与从未参加过体检的患者在肿瘤大小、残余肿瘤百分比和腋窝淋巴结转移频率方面没有差异。不定期参加该项目的女性预后最差。