Imachi M, Tsukamoto N, Matsuyama T, Nakano H
Department of Obstetrics and Gynecology, Kyushu University Faculty of Medicine, Fukuoka, Japan.
Gynecol Oncol. 1988 May;30(1):76-86. doi: 10.1016/0090-8258(88)90049-2.
Peritoneal cytology was obtained in 61 patients with carcinoma of the endometrium at the time of laparotomy. The incidence of positive peritoneal cytology was 23.0%. It increased as the clinical stage advanced. The incidence of positive peritoneal cytology in patients with well-differentiated carcinoma or superficial myometrial invasion was low. The rate of paraaortic lymph node metastasis was higher in patients with positive peritoneal cytology than in patients with negative peritoneal cytology. However, this trend was not recognized in pelvic lymph node metastasis. In the positive peritoneal cytology group, 64.3% had disease outside of the uterus, while in the negative group only 12.8%. The 2-year survival rate in patients with positive peritoneal cytology was 57.1% and it was 86.4% in patients with negative peritoneal cytology. It is concluded that the findings of positive peritoneal cytology is an important prognostic factor and routine peritoneal cytology should be obtained at the time of laparotomy in patients with carcinoma of the endometrium.
61例子宫内膜癌患者在剖腹手术时进行了腹腔细胞学检查。腹腔细胞学阳性率为23.0%。其随着临床分期的进展而增加。高分化癌或浅肌层浸润患者的腹腔细胞学阳性率较低。腹腔细胞学阳性患者的腹主动脉旁淋巴结转移率高于腹腔细胞学阴性患者。然而，盆腔淋巴结转移方面未发现此趋势。腹腔细胞学阳性组中，64.3%的患者子宫外有病变，而阴性组仅为12.8%。腹腔细胞学阳性患者的2年生存率为57.1%，腹腔细胞学阴性患者为86.4%。结论是腹腔细胞学阳性结果是一个重要的预后因素，子宫内膜癌患者在剖腹手术时应常规进行腹腔细胞学检查。
