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环糊精包覆金纳米颗粒(AuNP@CDs):从合成到应用

Cyclodextrin capped gold nanoparticles (AuNP@CDs): from synthesis to applications.

作者信息

Wang Yichuan, Han Yufen, Tan Xiaoling, Dai Yu, Xia Fan, Zhang Xiaojin

机构信息

Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, China.

出版信息

J Mater Chem B. 2021 Mar 21;9(11):2584-2593. doi: 10.1039/d0tb02857f. Epub 2021 Mar 5.

Abstract

As a multifunctional platform, cyclodextrin capped gold nanoparticles (AuNP@CDs) have attracted extensive attention due to their advantages of high specific surface area and high loading capacity. AuNP@CDs have a core-shell structure, retaining the advantages of the two materials. AuNPs act as the support for the monolayer assembly of CDs. Some functional molecules can enter the hydrophobic cavity of CD through the host-guest interaction. In this brief review, we discuss the strategies for the synthesis of AuNP@CDs depending on the type and order of bonding. Their applications in drug delivery, catalysis, detection and bioimaging are highlighted. We hope to further stimulate AuNP@CD related research.

摘要

作为一种多功能平台,环糊精包覆的金纳米粒子(AuNP@CDs)因其高比表面积和高负载能力的优点而受到广泛关注。AuNP@CDs具有核壳结构,保留了两种材料的优点。金纳米粒子作为环糊精单层组装的支撑体。一些功能分子可以通过主客体相互作用进入环糊精的疏水空腔。在这篇简短的综述中,我们根据键合的类型和顺序讨论了AuNP@CDs的合成策略。重点介绍了它们在药物递送、催化、检测和生物成像方面的应用。我们希望进一步推动与AuNP@CD相关的研究。

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