State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 310000, China.
ACS Appl Mater Interfaces. 2021 Mar 17;13(10):12359-12365. doi: 10.1021/acsami.0c21817. Epub 2021 Mar 5.
Developing the ultrathin membranes for high-performance separation still faces the challenge of both high permeance and selectivity. Herein, a large-area protein membrane was fabricated by the interfacial self-assembly of bovine serum albumin (BSA) and surfactants at the oil/water interface of emulsions. Benefiting from the ultrathin thickness and unique protein-surrounded tortuous channels, the membrane displays ultrahigh permeation flux and selective sieving capability for various molecules ranging from small dye molecules to proteins based on a dual filtration mechanism. More importantly, the rejection precision can also be reversibly regulated by the folding/unfolding transition of proteins to control the effective pore size of transport channels, even under a pressure-driven condition. This dynamically tunable ultrathin protein membrane combines the advantages of high permeance, selectivity, controllability, recyclability, and mechanical stability, which may create new opportunities for advanced applications in extended fields.
开发用于高性能分离的超薄膜仍然面临着高渗透性和选择性的双重挑战。在此，通过在乳液的油水界面处牛血清白蛋白（BSA）和表面活性剂的界面自组装，制备了大面积的蛋白质膜。得益于超薄厚度和独特的蛋白质包围的曲折通道，该膜在基于双重过滤机制的各种分子（从小染料分子到蛋白质）的超高渗透通量和选择性筛分能力方面表现出色。更重要的是，通过蛋白质的折叠/展开转变可以可逆地调节截留精度，以控制传输通道的有效孔径，即使在压力驱动的条件下也是如此。这种动态可调的超薄蛋白质膜结合了高渗透性、选择性、可控性、可回收性和机械稳定性的优点，可能为在更广泛的领域中的先进应用创造新的机会。
