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早期和中期近端胃癌患者食管残胃前壁吻合对术后反流和营养状况的影响。

Effect of Esophagus-Remnant Stomach Anterior Wall Anastomosis on Postoperative Reflux and Nutritional Status in Patients with Early- and Intermediate-Stage Proximal Gastric Cancer.

机构信息

Guangxi Clinical Research Center for Colorectal Cancer, Division of Colorectal & Anal Surgery, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China.

出版信息

J Laparoendosc Adv Surg Tech A. 2022 Mar;32(3):244-250. doi: 10.1089/lap.2021.0016. Epub 2021 Mar 5.

Abstract

To compare and analyze the incidence of postoperative reflux esophagitis (RE) in patients with early- and intermediate-stage proximal gastric cancer after proximal gastrectomy plus esophagus-remnant stomach anterior wall anastomosis with proper spacing between the reserved anastomotic stoma and the stump of the remnant stomach versus total gastrectomy plus Roux-en-Y anastomosis and to analyze the advantages and disadvantages of these anastomosis approaches. Hospitalization data of 23 patients with early- and intermediate-stage proximal gastric cancer were retrospectively analyzed. They were divided into an observation group who underwent proximal gastrectomy plus esophagus-remnant stomach anterior wall anastomosis with proper spacing between the reserved anastomotic stoma and the stump of the remnant stomach and a control group who underwent total gastrectomy plus Roux-en-Y anastomosis. Quality observation indicators were compared between the two groups. There was no statistically significant difference between the groups in the number of lymph nodes cleared or the recurrence rate at 12 months postoperatively. The incidence of postoperative RE was significantly lower in the observation group (25%) than in the control group (80%). The operation time, postoperative length of hospital stay, appetite change, body mass index, and hemoglobin level at 6 months postoperatively were significantly better in the observation group than in the control group ( < .05). Proximal gastrectomy plus esophagus-remnant stomach anterior wall anastomosis with proper spacing between the reserved anastomotic stoma and the stump of the remnant stomach can be used as a preferred surgical procedure for early- and mid-stage proximal gastric cancer.

摘要

目的

比较分析近端胃大部切除残胃前壁食管残端吻合加适当预留吻合口与残胃残端之间间距(观察组)与全胃切除 Roux-en-Y 吻合术(对照组)治疗早期和中期近端胃癌术后反流性食管炎(RE)的发生率,分析两种吻合术式的优缺点。

方法

回顾性分析 23 例早期和中期近端胃癌患者的住院资料,观察组患者行近端胃大部切除残胃前壁食管残端吻合加适当预留吻合口与残胃残端之间间距,对照组患者行全胃切除 Roux-en-Y 吻合术,比较两组患者的质量观察指标。

结果

两组患者的清扫淋巴结数目和术后 12 个月的复发率比较,差异均无统计学意义(P>.05);观察组术后 RE 发生率(25%)显著低于对照组(80%)(P<.05);观察组患者的手术时间、术后住院时间、食欲变化、术后 6 个月体质量指数和血红蛋白水平均明显优于对照组(P<.05)。

结论

近端胃大部切除残胃前壁食管残端吻合加适当预留吻合口与残胃残端之间间距可作为治疗早期和中期近端胃癌的首选术式。

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