University of Rochester Medical Center, Rochester, New York, USA.
Nutr Clin Pract. 2021 Apr;36(2):360-368. doi: 10.1002/ncp.10634. Epub 2021 Mar 5.
Fluid imbalance can occur quickly in older adults and in others who cannot express thirst or are in a setting where fluid status is not closely monitored. In tube-fed individuals receiving inadequate calories, severe malnutrition may occur in weeks to months, but improper water intake may lead to critical fluid imbalances in a matter of days. Simplistic equations frequently used to determine fluid needs in adults include milliliters per kilogram of body weight and milliliters per energy (kilocalories) consumed or per energy (kilocalories) need and variations of the Holliday-Segar formula. None of these fluid-requirement equations have been validated through evidenced-based science, and research investigations have revealed that they can grossly overestimate or underestimate fluid needs in the older adult. Clinicians need guidance to better estimate initial fluid needs for the older adult receiving tube feedings and to provide proper close monitoring afterward to avert preventable fluid imbalance-related hospital readmissions, morbidities, and mortalities in this patient population.
液体失衡在老年人和其他无法表达口渴感或液体状态未被密切监测的人群中可能会迅速发生。在接受热量不足的管饲人群中,严重的营养不良可能会在数周到数月内发生,但不当的水分摄入可能会在数天内导致严重的液体失衡。常用于确定成人液体需求的简化方程包括每公斤体重的毫升数和每消耗的能量(千卡)或每需要的能量(千卡)的毫升数,以及霍利迪-塞加尔公式的变体。这些液体需求方程都没有经过基于证据的科学验证,研究调查表明,它们可能会严重高估或低估老年人的液体需求。临床医生需要指导,以更好地估计接受管饲的老年人的初始液体需求,并在之后提供适当的密切监测,以避免可预防的与液体失衡相关的医院再入院、发病率和死亡率。