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巴基斯坦 2 型糖尿病患者不安腿综合征的患病率及其决定因素。

Prevalence and determinants of restless leg syndrome in type 2 diabetes mellitus (T2DM) in Pakistan.

机构信息

Department of Pharmacy, Punjab University College of Pharmacy, AllamaIqbal Campus, University of the Punjab, 54000, Lahore, Pakistan.

Saulat Institute of Pharmaceutical Sciences & Drug Research, Quaid-i-Azam University, Islamabad, Pakistan.

出版信息

Diabetes Metab Syndr. 2021 Mar-Apr;15(2):525-528. doi: 10.1016/j.dsx.2021.02.013. Epub 2021 Feb 13.

Abstract

BACKGROUND AND AIMS

Restless legs syndromes (RLS) are intrinsic sleeping disorder and its prevalence rate is 10-15% in general population but it is observed that prevalence rate is different in diabetes patients. Current study aims to find prevalence and determinants of RLS in people living with type 2 diabetes mellitus in Pakistan.

METHOD

A multicenter cross-sectional observational study was conducted in 388 diabetes patients attending daily diabetes clinics and teaching hospitals in Pakistan's twin city between August 2019 and February 2020. The chi-square test and linear regression were used to detect RLS-related factors in type 2 diabetes mellitus.

RESULTS

The prevalence of RLS found was; 3.1% patients with diabetes were suffering from very severe RLS, 23.5% from severe RLS, 34% from moderate RLS, 21.1% from mild RLS and 18.3% from non-RLS. Gender, age, education, blood glucose fasting (BSF), blood glucose random (BSR) and HBA1c were found to be significant predictors of RLS in patients with diabetes.

CONCLUSION

Policy makers can develop local interventions to curb the growing RLS prevalence by keeping in control the risk factors of RLS in people living with type 2 diabetes.

摘要

背景与目的

不宁腿综合征(RLS)是一种内在的睡眠障碍,其在普通人群中的患病率为 10-15%,但在糖尿病患者中观察到的患病率有所不同。本研究旨在探讨巴基斯坦 2 型糖尿病患者 RLS 的患病率及其相关决定因素。

方法

2019 年 8 月至 2020 年 2 月,在巴基斯坦双子城的 388 名接受日常糖尿病诊所和教学医院治疗的糖尿病患者中进行了一项多中心横断面观察性研究。采用卡方检验和线性回归分析检测 2 型糖尿病患者 RLS 的相关因素。

结果

研究发现 RLS 的患病率为:3.1%的糖尿病患者患有非常严重的 RLS,23.5%患有严重的 RLS,34%患有中度 RLS,21.1%患有轻度 RLS,18.3%患有非 RLS。性别、年龄、教育程度、空腹血糖(BSF)、随机血糖(BSR)和 HBA1c 是糖尿病患者 RLS 的显著预测因素。

结论

决策者可以通过控制 2 型糖尿病患者 RLS 的危险因素,制定地方干预措施来遏制 RLS 患病率的增长。

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