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实施护理经理组织及其与抗抑郁药物模式的关联:瑞典初级保健中心的基于登记的研究。

Implementation of a care manager organisation and its association with antidepressant medication patterns: a register-based study of primary care centres in Sweden.

机构信息

Social medicine, School of Public Health and Community Medicine, Institute of Medicine, The Sahlgenska Academy, University of Gothenburg, Goteborg, Sweden

Social medicine, School of Public Health and Community Medicine, Institute of Medicine, The Sahlgenska Academy, University of Gothenburg, Goteborg, Sweden.

出版信息

BMJ Open. 2021 Mar 5;11(3):e044959. doi: 10.1136/bmjopen-2020-044959.

Abstract

OBJECTIVE

To evaluate the implementation of a care manager organisation for common mental disorders and its association with antidepressant medication patterns on primary care centre (PCC) level, compared with PCCs without this organisation. Moreover, to determine whether a care manager organisation is associated with antidepressant medication patterns that is more in accordance with treatment guidelines.

DESIGN

Register-based study on PCC level.

SETTING

Primary care in Region Västra Götaland, Sweden.

PARTICIPANTS

All PCCs in the region. PCCs were analysed in three subgroups: PCCs with a care manager organisation during 2015 and 2016 (n=68), PCCs without the organisation (n=92) and PCCs that shifted to a care manager organisation during 2016 (n=42).

OUTCOME MEASURES

Proportion of inadequate medication users, defined as number of patients 18 years with a common mental disorder diagnosis receiving care at a PCC in the region during the study period and dispensed 1-179 defined daily doses (DDD) of antidepressants of total patients with at least 1 DDD. The outcome was analysed through generalised linear regression and a linear mixed-effects model.

RESULTS

Overall, all PCCs had about 30%-34% of inadequate medication users. PCCs with a care manager organisation had significantly lower proportion of inadequate medication users in 2016 compared with PCCs without (-6.4%, p=0.02). These differences were explained by higher proportions in privately run PCCs. PCCs that shifted to a care manager organisation had a significant decrease in inadequate medication users over time (p=0.01).

CONCLUSIONS

Public PCCs had a more consistent antidepressant medication pattern compared with private PCCs that gained more by introducing a care manager organisation. It was possible to document a significant decrease in inadequate medication users, notwithstanding that PCCs in the region followed the guidelines to a comparatively high extent regardless of present care manager organisation.

摘要

目的

评估在初级保健中心(PCC)层面实施常见精神障碍护理经理组织的情况,并将其与没有该组织的 PCC 相比,分析其与抗抑郁药物治疗模式的关联。此外,还确定护理经理组织是否与更符合治疗指南的抗抑郁药物治疗模式相关。

设计

基于 PCC 层面的注册研究。

地点

瑞典西约塔兰地区的基层医疗。

参与者

该地区所有的 PCC。根据以下三个亚组分析 PCC:2015 年至 2016 年期间有护理经理组织的 PCC(n=68)、没有该组织的 PCC(n=92)和 2016 年转为护理经理组织的 PCC(n=42)。

结果测量

不适当药物使用者的比例,定义为在研究期间在该地区接受 PCC 治疗的 18 岁以上患有常见精神障碍诊断的患者数量,以及接受至少 1 个 DDD(定义日剂量)抗抑郁药的患者比例。结果通过广义线性回归和线性混合效应模型进行分析。

结果

总体而言,所有 PCC 的不适当药物使用者比例约为 30%-34%。与没有护理经理组织的 PCC 相比,有护理经理组织的 PCC 在 2016 年的不适当药物使用者比例显著降低(-6.4%,p=0.02)。这些差异是由私营 PCC 中更高的比例解释的。转为护理经理组织的 PCC 的不适当药物使用者数量随着时间的推移显著减少(p=0.01)。

结论

与获得护理经理组织后获益更多的私营 PCC 相比,公立 PCC 的抗抑郁药物治疗模式更为一致。尽管该地区的 PCC 无论是否有护理经理组织,都遵循了指南,而且程度相对较高,但仍有可能记录到不适当药物使用者的显著减少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c079/7938985/a2f8a6a58168/bmjopen-2020-044959f01.jpg

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