Division of Neurology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Department of Oncology, Karmanos Cancer Institute, Detroit, Michigan, USA.
Muscle Nerve. 2021 Jun;63(6):909-913. doi: 10.1002/mus.27218. Epub 2021 Mar 16.
Increasing evidence suggests the utility of the submandibular approach for ultrasonography to detect tongue fasciculation in amyotrophic lateral sclerosis (ALS). We hypothesized that transoral motion-mode ultrasonography (TOMU) would be useful to detect tongue fasciculation in patients with ALS.
Patients with sporadic ALS showing clinically definite tongue fasciculation were enrolled, and the ultrasonography findings of patients' tongues on TOMU and ultrasonography by the conventional submandibular approach were analyzed.
Six patients with clinically definite ALS were enrolled in this study. Although small, irregular muscle movements of 5 to 10 mm in amplitude and 0.1 to 0.2 second in duration were detected in all patients by TOMU, similar muscle movements were detected in only two of the six patients by the submandibular approach.
TOMU appeared to be useful for detecting tongue fasciculation in ALS patients. Further study is needed to better determine its role as a diagnostic tool for ALS.
越来越多的证据表明，下颌下途径的超声检查在肌萎缩侧索硬化症（ALS）中检测舌肌束颤具有一定的作用。我们假设经口运动模式超声（TOMU）对检测 ALS 患者的舌肌束颤是有用的。
我们招募了表现出临床明确的舌肌束颤的散发性 ALS 患者，并对患者的舌部经 TOMU 和传统下颌下途径超声检查的超声检查结果进行了分析。
本研究共纳入了 6 名临床确诊的 ALS 患者。虽然经 TOMU 检测到所有患者的振幅为 5 至 10 毫米、持续时间为 0.1 至 0.2 秒的小而不规则的肌肉运动，但只有 6 名患者中的 2 名通过下颌下途径检测到了类似的肌肉运动。
TOMU 似乎可用于检测 ALS 患者的舌肌束颤。需要进一步研究以更好地确定其作为 ALS 诊断工具的作用。
