Aka E, Horo A, Koffi A, Fanny M, Didi-Kouko C, Nda G, Abouna A, Kone M
Teaching Hospital of Yopougon-Abidjan/Obstetrics and Gynecology Unit, University Félix Houphouët Boigny (FHB), Abidjan, Cote d'Ivoire.
University Félix Houphouët Boigny (FHB), Teaching Hospital of Treichville-Abidjan/Oncology Unit, Abidjan, Cote d'Ivoire.
Gynecol Obstet Fertil Senol. 2021 Sep;49(9):684-690. doi: 10.1016/j.gofs.2021.03.001. Epub 2021 Mar 4.
To present the results of the personalized care of Ivorian women suffering from breast cancer since the advent of immunohistochemistry in Côte d'Ivoire.
We carried out a single-center retrospective study at the Yopougon university hospital from January 2014 to December 2018. All women's breast cancer with complementary immunohistochemistry and treated at the Yopougon hospital center were selected. Standard descriptive statistical tests were used to describe patient and tumor characteristics, and univariate and multivariate analyzes were performed with a statistical significance set at a P-value of 0.05 using SPSS version 20.0.
The mean age of women is 48.27 years, SD (11.92). 50.88 % of the tumors were hormone-dependent. The triple negative subgroup was the most represented (43.28 %) followed by luminal A (35.42 %). Conservative treatment represented 18.51 % of cases. In the univariate analysis, the risk of developing a hormone-dependent cancer is statistically significant respectively in women with an education level removed OR=1.98 (P˂0.015) and with a wealthy salary OR=1.85 (P˂0.009). On the other hand, the high level of education (OR=0.44; P˂0.005), and the well-off salary condition (OR=0.59; P˂0.024) would be protective factors for the development of triple negative breast cancer. All these factors are not significant in multivariate analysis, whether for hormone-dependent or triple negative tumors.
The personalized care of breast cancer in our African context remains difficult and must take into account several medical and extra-medical parameters.
介绍自免疫组化技术在科特迪瓦出现以来，针对患有乳腺癌的科特迪瓦女性进行个性化护理的结果。
我们于2014年1月至2018年12月在约普贡大学医院开展了一项单中心回顾性研究。选取了所有在约普贡医院中心接受补充免疫组化治疗的女性乳腺癌患者。使用标准描述性统计测试来描述患者和肿瘤特征，并使用SPSS 20.0版本进行单变量和多变量分析，设定统计学显著性的P值为0.05。
女性的平均年龄为48.27岁，标准差为11.92。50.88%的肿瘤为激素依赖性。三阴性亚组占比最高（43.28%），其次是腔面A型（35.42%）。保守治疗占病例的18.51%。在单变量分析中，受教育程度低的女性发生激素依赖性癌症的风险具有统计学意义，OR = 1.98（P˂0.015），薪资高的女性OR = 1.85（P˂0.009）。另一方面，高学历（OR = 0.44；P˂0.005）和薪资优厚的条件（OR = 0.59；P˂0.024）将是三阴性乳腺癌发生的保护因素。对于激素依赖性或三阴性肿瘤，所有这些因素在多变量分析中均无显著性。
在我们非洲的背景下，乳腺癌的个性化护理仍然困难，必须考虑到几个医学和医学之外的参数。
