Duong T H, Furet Y, Lorette G, Barrabes A, Arbeille B, Combescot C
Laboratoire de parasitologie, Hôpital Trousseau C.H.U. Tours.
Med Trop (Mars). 1988 Jan-Mar;48(1):39-43.
After a review of the mechanisms of anti-schistosomal activity of praziquantel and the treatment of Schistosoma mekongi with this drug, the authors report two cases of Schistosoma mekongi treated with praziquantel with failure. Rectal mucosa biopsies are performed and eggs are present. Light microscopic, electron microscopic and on ultra-thin sections examination of these samples don't reveal morphological alterations of Schistosoma mekongi eggs after treatment.
在回顾了吡喹酮的抗血吸虫活性机制以及用该药物治疗湄公血吸虫病后，作者报告了两例用吡喹酮治疗湄公血吸虫病失败的病例。进行了直肠黏膜活检，发现有虫卵。对这些样本进行光镜、电镜及超薄切片检查，未发现治疗后湄公血吸虫虫卵有形态学改变。
