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希腊专业指南中 HIV 检测建议评估:推荐检测的错失机会和改进空间。

Assessment of HIV testing recommendations in Greek specialty guidelines: A missed opportunity and room for improvement for recommending testing.

机构信息

Department of Internal Medicine and Infectious Diseases, University General Hospital of Patras, Patra, Greece.

Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

AIDS Care. 2021 Oct;33(10):1312-1315. doi: 10.1080/09540121.2021.1876837. Epub 2021 Mar 7.

DOI:10.1080/09540121.2021.1876837
PMID:33678071
Abstract

HIV testing for individuals presenting with indicator conditions (ICs) including AIDS-defining conditions (ADCs) is explicitly recommended by European guidelines. We aimed to review specialty guidelines in Greece and assess if HIV was discussed and testing recommended. We reviewed European guidelines to produce a list of 25 ADCs and 48 ICs. We identified Greek guidelines for 11 of 25 (44%) ADCs and 30 of 48 (63%) ICs. In total, 47 guidelines were reviewed (range: 1-6 per condition); 11 (23%) for ADCs and 36 (77%) for ICs. Association with HIV was discussed in 7 of 11 (64%) ADC and 8 of 36 IC guidelines (22%), whereas HIV testing was appropriately recommended in two of 11 ADC (18%) and 10 of 36 IC guidelines (28%). Significant differences were found for the distribution of recommendations to test in both types of condition, with ICs having higher percentage of non-recommendation (50%,  < 0.05). No association was found between source of guideline or publication year and testing recommendation. Most guidelines for ICs and ADCs do not recommend testing. Specialists managing most ICs and ADCs may be unaware of the actual prevalence of undiagnosed HIV infection among their patients or the respective recommendations produced by HIV societies.

摘要

HIV 检测在出现指征性疾病(ICs)的个体中,包括艾滋病定义性疾病(ADCs),欧洲指南明确推荐。我们旨在审查希腊的专业指南,并评估是否讨论了 HIV 以及是否推荐了检测。我们审查了欧洲指南,列出了 25 种 ADC 和 48 种 IC。我们确定了 11 种 ADC(44%)和 30 种 IC(63%)的希腊指南。总共审查了 47 份指南(每种疾病的范围为 1-6 份);11 份 ADC(23%)和 36 份 IC(77%)。在 11 份 ADC 中有 7 份(64%)和 36 份 IC 指南中有 8 份(22%)讨论了与 HIV 的关联,而在 11 份 ADC 中有 2 份(18%)和 36 份 IC 指南中有 10 份(28%)适当推荐了 HIV 检测。在这两种情况下,检测的推荐分布存在显著差异,IC 中不推荐检测的比例更高(50%,<0.05)。未发现指南来源或出版年份与检测建议之间存在关联。大多数 IC 和 ADC 指南不建议进行检测。管理大多数 IC 和 ADC 的专家可能不知道他们的患者中未确诊 HIV 感染的实际流行率,也不知道 HIV 协会提出的各自建议。

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引用本文的文献

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Missed opportunities for early HIV diagnosis in Greece: The MORFEAS study, 2019 to 2021.希腊错失早期艾滋病毒诊断机会:2019 至 2021 年 MORFEAS 研究。
Euro Surveill. 2024 Nov;29(48). doi: 10.2807/1560-7917.ES.2024.29.48.2400138.
2
Enhancing indicator condition-guided HIV testing in Taiwan: a nationwide case-control study from 2009 to 2015.提升指标条件导向之 HIV 筛检于台湾:2009 至 2015 年全国性病例对照研究。
BMC Public Health. 2024 Apr 5;24(1):967. doi: 10.1186/s12889-024-18499-6.
3
National medical specialty guidelines of HIV indicator conditions in Europe lack adequate HIV testing recommendations: a systematic guideline review.
欧洲国家医学专业 HIV 指标疾病指南缺乏足够的 HIV 检测推荐:系统的指南审查。
Euro Surveill. 2022 Dec;27(48). doi: 10.2807/1560-7917.ES.2022.27.48.2200338.