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嗅觉标记蛋白的免疫细胞化学

Immunocytochemistry of the olfactory marker protein.

作者信息

Monti-Graziadei G A, Margolis F L, Harding J W, Graziadei P P

出版信息

J Histochem Cytochem. 1977 Dec;25(12):1311-6. doi: 10.1177/25.12.336785.

DOI:10.1177/25.12.336785
PMID:336785
Abstract

The olfactory marker protein has been localized, by means of immunohistochemical techniques in the primary olfactory neurons of mice. The olfactory marker protein is not present in the staminal cells of the olfactory neuroepithelium, and the protein may be regarded as indicative of the functional stage of the neurons. Our data indicate that the olfactory marker protein is present in the synaptic terminals of the olfactory neurons at the level of the olfactory bulb glomeruli. The postsynaptic profiles of both mitral and periglomerular cells are negative.

摘要

通过免疫组织化学技术已将嗅觉标记蛋白定位在小鼠的初级嗅觉神经元中。嗅觉标记蛋白不存在于嗅觉神经上皮的干细胞中,该蛋白可被视为神经元功能阶段的指示物。我们的数据表明,嗅觉标记蛋白存在于嗅球小球水平的嗅觉神经元的突触终末。二尖瓣细胞和球周细胞的突触后轮廓均为阴性。

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1
Immunocytochemistry of the olfactory marker protein.嗅觉标记蛋白的免疫细胞化学
J Histochem Cytochem. 1977 Dec;25(12):1311-6. doi: 10.1177/25.12.336785.
2
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Immunohistopathology of human olfactory epithelium, nerve and bulb.人类嗅上皮、神经和嗅球的免疫组织病理学
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Compartmental organization of the olfactory bulb glomerulus.嗅球肾小球的分区组织。
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Intraglomerular dendritic link connected by gap junctions and chemical synapses in the mouse main olfactory bulb: electron microscopic serial section analyses.小鼠主嗅球中通过缝隙连接和化学突触相连的肾小球内树突连接:电子显微镜连续切片分析
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