Department of Nephrology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2021 Jan 28;46(1):104-107. doi: 10.11817/j.issn.1672-7347.2021.190258.
Dermatomyositis (DM) is a kind of idiopathic inflammatory myopathy characterized by chronic proximal skeletal muscle weakness and unique skin lesions. However, DM with exfoliation of esophageal mucosa is rare. A 36-year-old male patient complained of muscular soreness of extremities, dysphagia, and pharyngalgia was diagnosed with DM with exfoliation of esophageal mucosa. After treatment with glucocorticoid, immunosuppressant, acupuncture, and endoscopic submucosal dissection (ESD), the above symptoms were disappeared. During the 3-year follow-up period, the results of routine physical examination, laboratory examination, gastroscopy, and imaging examination were normal. High-dose of corticosteroid is needed in the initial treatment, but it must be reduced regularly to avoid adverse reactions. Acupuncture and ESD are also effective as adjuvant therapy.
皮肌炎（DM）是一种特发性炎症性肌病，其特征为慢性近端骨骼肌肉无力和独特的皮肤损伤。然而，伴有食管黏膜剥脱的 DM 较为罕见。一位 36 岁男性患者因四肢肌肉酸痛、吞咽困难和咽痛就诊，被诊断为伴有食管黏膜剥脱的 DM。经糖皮质激素、免疫抑制剂、针灸和内镜黏膜下剥离术（ESD）治疗后，上述症状消失。在 3 年的随访期间，常规体检、实验室检查、胃镜和影像学检查结果均正常。初始治疗需要大剂量的皮质类固醇，但必须定期减量以避免不良反应。针灸和 ESD 也作为辅助治疗有效。
