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对长期接受锂盐维持治疗的双相情感障碍患者锂相关知识和态度的评估。

Assessment of lithium-related knowledge and attitudes among patients with bipolar disorder on long-term lithium maintenance treatment.

作者信息

Kumar Saurabh, Singh Swarndeep, Mahal Pankaj, Vishwakarma Anuranjan, Deep Raman

机构信息

Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Psychiatry. 2020 Sep-Oct;62(5):577-581. doi: 10.4103/psychiatry.IndianJPsychiatry_339_19. Epub 2020 Oct 10.

DOI:10.4103/psychiatry.IndianJPsychiatry_339_19
PMID:33678841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7909029/
Abstract

BACKGROUND

Gaps in lithium-related knowledge among bipolar disorder (BD) patients on lithium prophylaxis may pose safety concerns and could adversely influence attitudes to lithium.

OBJECTIVE

To assess the lithium-related knowledge and attitudes among patients with BD.

MATERIALS AND METHODS

This was a cross-sectional, observational study assessing euthymic, adult outpatients with BD on lithium prophylaxis (≥1 year) using a semi-structured pro forma, lithium questionnaire for knowledge, lithium attitude questionnaire (LAQ), and medication adherence rating scale (MARS).

RESULTS

Descriptive analysis revealed several deficits in knowledge, including lack of critical safety information or need for periodic blood tests. Lower knowledge group had significantly more negative attitudes. Favorable attitude toward lithium (lower LAQ score) was significantly associated with the number of psychiatric follow-ups in the last year and MARS score.

CONCLUSION

There were critical deficits in lithium-related knowledge among the patients. Lower lithium knowledge was associated with negative lithium attitudes. Educative interventions should be delivered periodically to regular lithium users.

摘要

背景

接受锂盐预防性治疗的双相情感障碍(BD)患者在锂盐相关知识方面存在差距,这可能引发安全担忧,并可能对其对锂盐的态度产生不利影响。

目的

评估BD患者的锂盐相关知识和态度。

材料与方法

这是一项横断面观察性研究,使用半结构化表格、锂盐知识问卷、锂盐态度问卷(LAQ)和药物依从性评定量表(MARS),对接受锂盐预防性治疗(≥1年)的成年BD门诊康复期患者进行评估。

结果

描述性分析揭示了知识方面的几个缺陷,包括缺乏关键的安全信息或定期血液检查的必要性。知识水平较低的组态度明显更消极。对锂盐的积极态度(较低的LAQ评分)与过去一年的精神科随访次数和MARS评分显著相关。

结论

患者在锂盐相关知识方面存在关键缺陷。锂盐知识水平较低与对锂盐的消极态度相关。应定期对长期使用锂盐的患者进行教育干预。

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本文引用的文献

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Asian J Psychiatr. 2019 Dec;46:34-40. doi: 10.1016/j.ajp.2019.09.015. Epub 2019 Sep 23.
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World Psychiatry. 2014 Feb;13(1):90-2. doi: 10.1002/wps.20091.
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