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Editorial: Memory T Cells in Chronic Infections and Tumors.

作者信息

Hofmann Maike, Jandus Camilla, Lee Lian Ni, Utzschneider Daniel T

机构信息

Clinic of Internal Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

出版信息

Front Immunol. 2021 Feb 17;12:656010. doi: 10.3389/fimmu.2021.656010. eCollection 2021.

Abstract
摘要

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本文引用的文献

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Memory-like HCV-specific CD8 T cells retain a molecular scar after cure of chronic HCV infection.
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Early precursor T cells establish and propagate T cell exhaustion in chronic infection.
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TOX is expressed by exhausted and polyfunctional human effector memory CD8 T cells.
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Precursor exhausted T cells: key to successful immunotherapy?
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Subsets of exhausted CD8 T cells differentially mediate tumor control and respond to checkpoint blockade.
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