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容积调强弧形放疗（VMAT）：一种现代放疗技术——单机构经验

Volumetric Modulated Arc Therapy (VMAT): A modern radiotherapy technique - A single institutional experience.

作者信息

Rashid Azhar, Ahmad Zaeem, Memon Muhammad Ali, Hashim Abdul Sattar M

机构信息

Dr. Azhar Rashid, MBBS, FCPS, MSc. Clinical & Radiation Oncologist, Department of Radiation Oncology (Stereotactic Radiosurgery), Neurospinal & Cancer Care Institute (NCCI), M.A Jinnah Road, Saddar, Karachi, Pakistan.

Mr. Zaeem Ahmed, MSc Physics Medical Physicist, Department of Radiation Oncology (Stereotactic Radiosurgery), Neurospinal & Cancer Care Institute (NCCI), M.A Jinnah Road, Saddar, Karachi, Pakistan.

出版信息

Pak J Med Sci. 2021 Mar-Apr;37(2):355-361. doi: 10.12669/pjms.37.2.2647.

DOI:10.12669/pjms.37.2.2647
PMID:33679913
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7931288/
Abstract

OBJECTIVE

To evaluate VMAT plans for conformity and homogeneity of radiation dose to the target in order to share our experience as a pioneering institute to use VMAT technology in Pakistan.

METHODS

Since December 2014 to January 2018, 530 patients of various anatomical sites were treated by VMAT technique at Neurospinal Cancer Care Institute (NCCI) Karachi Pakistan. ERGO++ planning system (Version 1.7.2) was used to develop VMAT plans with single or multiple arcs by the rotation of couch and gantry. The plans were evaluated by calculating Conformity Index (CI) and Homogeneity Index (HI) and critical organ (OARs) doses of individual tumor sites.

RESULTS

The average CI of various sites was 1.4 (range: 1.0-2.0) and average HI of various sites was 1.20 (range: 1.07-1.374), respective critical organ doses were adequately achieved.

CONCLUSIONS

VMAT treatment planning technique showed good conformal and homogeneous target coverage with sparing of organs at risk and reduced treatment delivery time. With these features, safety of VMAT technique may allow its routine clinical use, though it is still under investigation in many areas.

摘要

目的

评估容积调强弧形放疗（VMAT）计划对靶区辐射剂量的适形性和均匀性，以便分享我们作为巴基斯坦率先使用VMAT技术的机构的经验。

方法

自2014年12月至2018年1月，巴基斯坦卡拉奇神经脊髓癌症护理研究所（NCCI）使用VMAT技术治疗了530例不同解剖部位的患者。使用ERGO++计划系统（版本1.7.2）通过治疗床和机架的旋转来制定单弧或多弧的VMAT计划。通过计算适形指数（CI）、均匀性指数（HI）以及各个肿瘤部位的危及器官（OARs）剂量来评估这些计划。

结果

各个部位的平均CI为1.4（范围：1.0 - 2.0），各个部位的平均HI为1.20（范围：1.07 - 1.374），相应的危及器官剂量也得到了充分实现。

结论

VMAT治疗计划技术显示出良好的靶区适形性和均匀覆盖，同时能够保护危及器官并缩短治疗时间。具备这些特性，VMAT技术的安全性或许允许其在临床常规使用，尽管在许多方面仍在研究之中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86c6/7931288/6cfbf1a265b8/PJMS-37-355-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86c6/7931288/98dd973002ee/PJMS-37-355-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86c6/7931288/b1c4d6db4746/PJMS-37-355-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86c6/7931288/4c8d14071d3e/PJMS-37-355-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86c6/7931288/6cfbf1a265b8/PJMS-37-355-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86c6/7931288/98dd973002ee/PJMS-37-355-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86c6/7931288/b1c4d6db4746/PJMS-37-355-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86c6/7931288/4c8d14071d3e/PJMS-37-355-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86c6/7931288/6cfbf1a265b8/PJMS-37-355-g004.jpg

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