Wilson's Disease and Iron Overload: Pathophysiology and Therapeutic Implications.
作者信息
Pak Kevin, Ordway Sarah, Sadowski Brett, Canevari Margaux, Torres Dawn
机构信息
Department of Medicine Division of General Internal Medicine Walter Reed National Military Medical Center Bethesda MD.
Department of Medicine Division of Gastroenterology and Hepatology Walter Reed National Military Medical Center Bethesda MD.
出版信息
Clin Liver Dis (Hoboken). 2021 Feb 28;17(2):61-66. doi: 10.1002/cld.986. eCollection 2021 Feb.
Abstract
摘要
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Zinc induces iron uptake and DMT1 expression in Caco-2 cells via a PI3K/IRP2 dependent mechanism.锌通过 PI3K/IRP2 依赖的机制诱导 Caco-2 细胞中铁的摄取和 DMT1 的表达。
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