Lázaro-Martínez José Luis, García-Madrid Marta, García-Álvarez Yolanda, Álvaro-Afonso Francisco Javier, Sanz-Corbalán Irene, García-Morales Esther
Diabetic Foot Unit, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Edificio Facultad de Medicina, Pabellón 1. Avda. Complutense s/n, Madrid, 28040, Spain.
J Clin Orthop Trauma. 2020 Dec 15;16:86-98. doi: 10.1016/j.jcot.2020.12.014. eCollection 2021 May.
Osteomyelitis (OM) is the most frequent infection associated with diabetic foot ulcers (DFU) that typically involve the forefoot, the most common location of DFU. Conservative surgical procedures could be attractive alternative that reduces minor and major amputations and avoid future recurrence thus preserving the functionally of the foot. This review aimed to analyze and describe the current evidence on conservative diabetic foot osteomyelitis (DFO) surgical procedures depending on DFU location and indications. A narrative revision of the evidence was carried out by searching Medline through PubMed databases from inception to late July 2020 to identify retrospective, prospective, and randomized controlled trials pertaining to conservative DFO procedures on the forefoot. Seven types of conservative surgical procedures for DFO treatment in the forefoot are described in this review: (1) partial or total distal phalangectomy, (2) arthroplasty of the proximal or distal interphalangeal joint, (3) distal Syme amputation, (4) percutaneous flexor tenotomy, (5) sesamoidectomy, (6) arthroplasty of the metatarsophalangeal joint, and (7) metatarsal head resection. When indicated, conservative surgery for DFUs in patients with chronic forefoot OM is a safe and effective option that increases the chances of healing and reduces the possibility of limb loss and death compared with radical amputation procedures. Since a lack of sufficient evidence supporting this procedure exists, future investigations should be focused on the random clinical trial (RCT) design. The results of prospective trials could help surgeons select the appropriate procedure in each case in order to minimize complications.
骨髓炎(OM)是与糖尿病足溃疡(DFU)相关的最常见感染,DFU通常累及前足,这是DFU最常见的部位。保守性外科手术可能是一种有吸引力的替代方案,可减少大、小截肢,并避免未来复发,从而保留足部功能。本综述旨在分析和描述根据DFU位置和适应症进行的保守性糖尿病足骨髓炎(DFO)外科手术的现有证据。通过在PubMed数据库中检索Medline,从创建到2020年7月下旬进行了证据的叙述性修订,以识别与前足保守性DFO手术相关的回顾性、前瞻性和随机对照试验。本综述描述了七种用于治疗前足DFO的保守性外科手术:(1)部分或全部远节趾骨切除术,(2)近端或远端指间关节成形术,(3)Syme远端截肢术,(4)经皮屈肌腱切断术,(5)籽骨切除术,(6)跖趾关节成形术,以及(7)跖骨头切除术。在有指征时,对于慢性前足OM患者的DFU进行保守性手术是一种安全有效的选择,与根治性截肢手术相比,可增加愈合机会并降低肢体丧失和死亡的可能性。由于缺乏支持该手术的充分证据,未来的研究应集中在随机临床试验(RCT)设计上。前瞻性试验的结果可帮助外科医生在每种情况下选择合适的手术,以尽量减少并发症。