Aragón-Sánchez Javier, Víquez-Molina Gerardo, López-Valverde María E, Rojas-Bonilla José M, Murillo-Vargas Christian
La Paloma Hospital, Las Palmas de Gran Canaria, Spain.
San Juan de Dios Hospital, San José, Costa Rica.
Int J Low Extrem Wounds. 2023 Jun;22(2):328-331. doi: 10.1177/15347346211009403. Epub 2021 Apr 23.
Conservative surgery of diabetic foot osteomyelitis (DFO) in which bone infection is removed without amputation could minimize the biomechanical changes associated with foot surgery. We hypothesize that patients who undergo conservative surgery will have a longer survival time without recurrence of foot ulcers and further amputations than those who undergo any type of amputation to treat DFO. We assessed a retrospective cohort of 108 patients who underwent surgery for DFO from January 2011 to December 2012. Patients were followed-up until May 2020. Reulceration and reamputation-free survival times were plotted using the Kaplan-Meier method and were calculated from the date of first surgery to recurrence, new amputation, or end of the study. A stratified log rank was used to study differences among groups. Cumulative survival without recurrences at 1, 5, and 8 years was 95%, 36%, and 29%, respectively, in patients who underwent conservative surgery and 95%, 43%, and 30%, respectively, in those undergoing amputation. Cumulative survival without a new amputation at 1, 5, and 8 years was 100%, 80%, and 80%, respectively, in patients who underwent conservative surgery and 98%, 82%, and 69%, respectively, in those undergoing amputation. No differences were found regarding either recurrence (log rank, = .98) or new amputations (log rank, = .64). In conclusion, conservative surgery is as safe as amputation to arrest bone infection in the feet of patients with diabetes. Conservative surgery was not associated with a lower rate of recurrence and new amputations than those patients who underwent amputations.
糖尿病足骨髓炎(DFO)的保守手术是指在不进行截肢的情况下清除骨感染,这种手术可以将与足部手术相关的生物力学变化降至最低。我们假设,与接受任何类型截肢手术治疗DFO的患者相比,接受保守手术的患者无足部溃疡复发和进一步截肢的生存时间更长。我们评估了一组回顾性队列,该队列由2011年1月至2012年12月期间接受DFO手术的108例患者组成。对患者进行随访至2020年5月。使用Kaplan-Meier方法绘制无再溃疡和无再次截肢的生存时间,并从首次手术日期计算至复发、新截肢或研究结束。采用分层对数秩检验研究组间差异。接受保守手术的患者1年、5年和8年无复发的累积生存率分别为95%、36%和29%,接受截肢手术的患者分别为95%、43%和30%。接受保守手术的患者1年、5年和8年无新截肢的累积生存率分别为100%、80%和80%,接受截肢手术的患者分别为98%、82%和69%。在复发(对数秩检验,P = 0.98)或新截肢(对数秩检验,P = 0.64)方面均未发现差异。总之,在控制糖尿病患者足部骨感染方面,保守手术与截肢手术一样安全。与接受截肢手术的患者相比,保守手术的复发率和新截肢率并不更低。