Pontifícia Universidade Católica de Campinas, Programa de Pós-Graduação em Ciências da Saúde, Campinas SP, Brazil.
Pontifícia Universidade Católica de Campinas, Faculdade de Medicina, Campinas SP, Brazil.
Arq Neuropsiquiatr. 2021 Apr;79(4):310-314. doi: 10.1590/0004-282X-ANP-2020-0517.
The COVID-19 pandemic and social distancing can have adverse impacts on adult people with epilepsy (PWE).
To investigate the seizure frequency, the perceived well-being, and the presence of anxiety symptoms in PWE during the COVID-19 pandemic period.
Data from a questionnaire on the repercussions of COVID-19 were analyzed in relation to the clinical variables of 114 PWE, with a significance level of p<0.05.
There were 26 cases of COVID-19 in PWE and/or family members (22.8%). During the pandemic period, 11 PWE (9.6%) reported an increase in seizures, but unrelated to COVID-19. Also, the number of crises in PWE with previous depressive disorders increased, with differences between epilepsies. Symptoms of depression, impaired well-being, and concern for their lifestyle were significant in PWE with a previous diagnosis of depression. Impaired well-being, increased anxiety, nervousness, and tiredness, and the concern with being infected were mentioned by a high number of PWE in the pandemic.
Seizure frequency increased during the pandemic period, a finding associated with clinical variables of epilepsy. PWE with depression had worse perceived well-being. Changes in well-being and increased anxiety and nervousness were frequent in the pandemic.
COVID-19 大流行和社交隔离会对成年癫痫患者（PWE）产生不利影响。
调查 COVID-19 大流行期间 PWE 的癫痫发作频率、感知健康状况和焦虑症状的发生情况。
分析了 114 例 PWE 的 COVID-19 影响问卷调查数据，与临床变量相关，具有统计学意义的 p 值<0.05。
PWE 及其家庭成员中有 26 例（22.8%）COVID-19 病例。在大流行期间，11 例 PWE（9.6%）报告癫痫发作增加，但与 COVID-19 无关。此外，有抑郁障碍病史的 PWE 癫痫发作次数增加，不同癫痫类型之间存在差异。有抑郁病史的 PWE 出现抑郁症状、健康状况受损和对生活方式的担忧更为明显。在大流行期间，许多 PWE 出现健康状况受损、焦虑、紧张和疲劳增加以及对感染的担忧。
大流行期间癫痫发作频率增加，这与癫痫的临床变量有关。有抑郁病史的 PWE 感知健康状况更差。在大流行期间，健康状况的变化和焦虑、紧张情绪的增加较为常见。
