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胎儿手术的母体和胎儿麻醉。

Maternal and fetal anaesthesia for fetal surgery.

机构信息

Department of Obstetric Anaesthesia, University College Hospital, London, UK.

Department of Obstetrics and Fetal Medicine, University College Hospital, London, UK.

出版信息

Anaesthesia. 2021 Apr;76 Suppl 4:63-68. doi: 10.1111/anae.15423.

DOI:10.1111/anae.15423
PMID:33682103
Abstract

Over the last three decades, advances in early diagnosis of fetal anomalies, imaging and surgical techniques have led to a huge expansion in fetal surgery. A small number of specialist centres perform fetal surgery, which involves high-risk anaesthesia for the mother and fetus. The anaesthetist plays an integral role within the large multispecialty and multidisciplinary team, involved in planning and delivering care for complex surgical procedures. This article reviews three fetal surgical procedures, congenital diaphragmatic hernia, myelomeningocele repair and ex-utero intrapartum treatment for airway obstruction. The underlying fetal pathology, surgical management, anaesthetic considerations and risks for both the mother and fetus are described for each. Fundamental to this is the understanding that clear communication and collaboration between all team members is vital to ensure successful outcomes of patients, the mother and the fetus.

摘要

在过去的三十年中,胎儿畸形的早期诊断、影像学和手术技术的进步导致了胎儿手术的巨大扩展。少数专业中心开展胎儿手术,这涉及到母亲和胎儿的高风险麻醉。麻醉师在大型多专业和多学科团队中发挥着不可或缺的作用,参与复杂手术的规划和提供护理。本文回顾了三种胎儿手术,即先天性膈疝、脊髓脊膜膨出修复和子宫外产时气道阻塞治疗。描述了每种手术的潜在胎儿病理学、手术管理、麻醉注意事项以及对母亲和胎儿的风险。至关重要的是,要理解所有团队成员之间的清晰沟通和协作对于确保患者、母亲和胎儿的治疗成功至关重要。

相似文献

1
Maternal and fetal anaesthesia for fetal surgery.胎儿手术的母体和胎儿麻醉。
Anaesthesia. 2021 Apr;76 Suppl 4:63-68. doi: 10.1111/anae.15423.
2
[Advances in fetal surgery].[胎儿外科手术的进展]
Lakartidningen. 2017 Aug 29;114:EM6E.
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Fetal anesthesia: intrauterine therapies and immediate postnatal anesthesia for noncardiac surgical interventions.胎儿麻醉:子宫内治疗和非心脏手术干预的即刻产后麻醉。
Curr Opin Anaesthesiol. 2020 Jun;33(3):368-373. doi: 10.1097/ACO.0000000000000862.
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Ex utero intrapartum therapy.产时宫外治疗
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Alterations in maternal-fetal cellular trafficking after fetal surgery.胎儿手术后母胎细胞转运的改变。
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Perinatal management of the anticipated difficult airway.预期困难气道的围产期管理。
Semin Fetal Neonatal Med. 2023 Oct;28(5):101485. doi: 10.1016/j.siny.2023.101485. Epub 2023 Nov 20.
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The ex utero intrapartum treatment procedure: Looking back at the EXIT.子宫外产时治疗程序:回顾子宫外产时处理术
J Pediatr Surg. 2004 Mar;39(3):375-80; discussion 375-80. doi: 10.1016/j.jpedsurg.2003.11.011.
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Minimally Invasive Fetal Surgery.微创胎儿手术
Clin Perinatol. 2017 Dec;44(4):729-751. doi: 10.1016/j.clp.2017.08.001. Epub 2017 Sep 23.
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The ex utero intrapartum treatment (EXIT) procedure for fetal head and neck masses.胎儿头颈部肿块的产时宫外治疗(EXIT)手术
AORN J. 2009 Nov;90(5):661-72; quiz 673-6. doi: 10.1016/j.aorn.2009.06.001.
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Fetal surgery: a critical review.胎儿外科手术:批判性综述。
Pediatr Surg Int. 2017 Apr;33(4):421-433. doi: 10.1007/s00383-016-4044-5. Epub 2017 Jan 5.

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Front Pediatr. 2025 Jul 17;13:1601963. doi: 10.3389/fped.2025.1601963. eCollection 2025.
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Trends in research related to fetal therapy from 2012 to 2022: a bibliometric analysis.2012年至2022年胎儿治疗相关研究趋势:一项文献计量分析
Front Pediatr. 2024 Jan 4;11:1288660. doi: 10.3389/fped.2023.1288660. eCollection 2023.
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Maternal and obstetric outcomes after Ex-Utero Intrapartum Treatment (EXIT): a single center experience.
体外分娩期宫内治疗(EXIT)后的母婴结局:单中心经验。
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Multiple sevoflurane exposures during mid-trimester induce neurotoxicity in the developing brain initiated by 15LO2-Mediated ferroptosis.多次七氟醚暴露于妊娠中期会诱发由 15LO2 介导的铁死亡引发的发育中大脑的神经毒性。
CNS Neurosci Ther. 2023 Oct;29(10):2972-2985. doi: 10.1111/cns.14236. Epub 2023 Jun 7.
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Recent advances in anaesthesia for intrauterine and foetal surgery.宫内和胎儿手术麻醉的最新进展
Indian J Anaesth. 2023 Jan;67(1):11-18. doi: 10.4103/ija.ija_964_22. Epub 2023 Jan 21.