University Hospital of Wales, Cardiff, UK.
Morriston Hospital, Swansea, UK.
Ann R Coll Surg Engl. 2021 Apr;103(4):250-254. doi: 10.1308/rcsann.2020.7128. Epub 2021 Mar 8.
The COVID-19 pandemic stimulated a national lockdown in the UK. The public were advised to avoid unnecessary hospital attendances and health professionals were advised to avoid aerosol-generating procedures wherever possible. The authors hypothesised that these measures would result in a reduction in the number of patients presenting to hospital with acute appendicitis and alter treatment choices.
A multicentred, prospective observational study was undertaken during April 2020 to identify adults treated for acute appendicitis. Searches of operative and radiological records were performed to identify patients treated during April 2018 and April 2019 for comparison.
A total of 190 patients were treated for acute appendicitis pre-lockdown compared with 64 patients treated during lockdown. Patients treated during the pandemic were more likely to have a higher American Society of Anesthesiology (ASA) score ( = 0.049) and to have delayed their presentation to hospital (2 versus 3 days, = 0.03). During the lockdown, the use of computed tomography (CT) increased from 36.3% to 85.9% ( < 0.001), the use of an antibiotic-only approach increased from 6.2% to 40.6% ( < 0.001) and the rate of laparoscopic appendicectomy reduced from 85.3% to 17.2% ( < 0.001). The negative appendicectomy rate decreased from 21.7% to 7.1% during lockdown (< 0.001).
The COVID-19 lockdown was associated with a decreased incidence of acute appendicitis and a significant shift in the management approach. The increased use of CT allows the identification of simple appendicitis for conservative treatment and decreases the negative appendicectomy rate.
COVID-19 大流行促使英国实行全国封锁。建议公众避免不必要的医院就诊,卫生专业人员尽可能避免产生气溶胶的操作。作者假设这些措施会导致因急性阑尾炎而到医院就诊的患者数量减少,并改变治疗选择。
在 2020 年 4 月进行了一项多中心、前瞻性观察性研究,以确定接受急性阑尾炎治疗的成年人。对手术和放射记录进行了搜索,以确定在 2018 年 4 月和 2019 年 4 月接受治疗的患者进行比较。
在封锁前,共有 190 例患者接受了急性阑尾炎治疗,而在封锁期间有 64 例患者接受了治疗。在大流行期间接受治疗的患者更有可能具有更高的美国麻醉医师协会(ASA)评分( = 0.049),并且延迟了到医院就诊的时间(2 天对 3 天, = 0.03)。在封锁期间,计算机断层扫描(CT)的使用从 36.3%增加到 85.9%( < 0.001),仅使用抗生素的方法从 6.2%增加到 40.6%( < 0.001),腹腔镜阑尾切除术的比率从 85.3%降至 17.2%( < 0.001)。在封锁期间,阴性阑尾切除术的比例从 21.7%降至 7.1%( < 0.001)。
COVID-19 封锁与急性阑尾炎的发病率降低以及管理方法的重大转变有关。CT 的广泛应用可以识别出简单的阑尾炎进行保守治疗,并降低阴性阑尾切除术的比例。