Corpataux Noé, Brugger Nicolas, Hunziker Lukas, Reineke David, Windecker Stephan, Vahanian Alec, Praz Fabien
Department of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.
Department of Cardiovascular Surgery, Bern University Hospital, University of Bern, Bern, Switzerland.
Expert Rev Med Devices. 2021 Mar;18(3):261-272. doi: 10.1080/17434440.2021.1899804. Epub 2021 Mar 26.
: Secondary mitral regurgitation (SMR) is one of the most common valvulopathies and is associated with poor prognosis. Over the past years, medical management and mitral valve repair options have rapidly evolved offering new opportunities for a wide range of patients.: We provide an up-to-date review of the value of medical and transcatheter mitral valve leaflet approximation for SMR integrating the results of most recent trials and putting their findings into clinical perspective.: Treatment of SMR requires a multidisciplinary approach with a long-term perspective. After optimization of medical treatment, transcatheter mitral valve repair should be considered in patients with persisting symptomatic severe SMR to improve symptoms and prognosis.
继发性二尖瓣反流（SMR）是最常见的瓣膜病之一，且与预后不良相关。在过去几年中，药物治疗和二尖瓣修复方案迅速发展，为众多患者带来了新的机遇。我们结合最新试验结果并将其研究结果置于临床背景下，对药物治疗和经导管二尖瓣瓣叶靠拢术治疗SMR的价值进行了最新综述。治疗SMR需要采取具有长期视角的多学科方法。在优化药物治疗后，对于持续存在症状性重度SMR的患者，应考虑行经导管二尖瓣修复术以改善症状和预后。
