University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Kentucky Injury Prevention and Research Center, University of Kentucky, Lexington, Kentucky, USA.
J Rural Health. 2022 Jan;38(1):161-170. doi: 10.1111/jrh.12567. Epub 2021 Mar 8.
The goal of this study was to evaluate how rural/urban status and other risk factors alter women's odds of severe maternal morbidity (SMM) at delivery.
This study used 48,608 Kentucky resident delivery hospitalization records from 2017. We used multiple logistic regression with interaction terms to evaluate the moderating effect of rural/urban residence with other risk factors. We reported adjusted odds ratios (aORs) and 95% confidence intervals (CIs) as measures for association with the outcome of SMM at delivery.
The percentage of delivery hospitalizations with SMM was higher for women with rural (2.4%) versus metro (1.1%) or metro-adjacent (1.5%) residence (p < .001). Rural status moderated the effect of anemia on SMM. The aOR for SMM for women with anemia versus those without was 8.56 (CI: 4.89-14.97) in rural areas, two times higher than in metro areas (aOR 3.87; CI: 3.09-4.86). Kentucky Appalachian region (aOR 1.90; CI: 1.46-2.47), Black race (aOR 1.30; CI: 1.02-1.66), history of cesarean section (aOR 1.28; CI: 1.07-1.52), hypertension (aOR 10.55; CI: 5.67-19.62), and opioid use (aOR 1.72; CI: 1.19-2.47) were significantly associated with SMM.
Rural women in Kentucky are at an increased risk for SMM. Quality and safety programming should specifically address the needs of isolated subpopulations. Women living in rural areas are more likely to experience SMM given an anemia diagnosis. The underlying cause and clinical management of anemia may differ between rural and urban areas.
本研究旨在评估农村/城市地位和其他风险因素如何改变女性分娩时严重产妇发病率(SMM)的几率。
本研究使用了 2017 年来自肯塔基州的 48608 名居民分娩住院记录。我们使用带有交互项的多变量逻辑回归来评估农村/城市居住与其他风险因素的调节作用。我们报告了调整后的优势比(aOR)和 95%置信区间(CI)作为与分娩时 SMM 结局相关的指标。
与城市(1.1%)或城市毗邻地区(1.5%)相比,农村地区(2.4%)的分娩住院患者 SMM 发生率更高(p<.001)。农村状况调节了贫血对 SMM 的影响。与无贫血的女性相比,农村地区贫血女性的 SMM 比值比(OR)为 8.56(95%CI:4.89-14.97),是城市地区的两倍(OR 3.87;95%CI:3.09-4.86)。肯塔基州阿巴拉契亚地区(OR 1.90;95%CI:1.46-2.47)、黑人种族(OR 1.30;95%CI:1.02-1.66)、剖宫产史(OR 1.28;95%CI:1.07-1.52)、高血压(OR 10.55;95%CI:5.67-19.62)和阿片类药物使用(OR 1.72;95%CI:1.19-2.47)与 SMM 显著相关。
肯塔基州的农村女性发生 SMM 的风险增加。质量和安全计划应专门针对孤立的亚人群的需求。如果诊断为贫血,生活在农村地区的女性更有可能经历 SMM。农村和城市地区贫血的根本原因和临床管理可能不同。