Department of Neurology, Duke University, Durham, NC, USA.
Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.
Amyotroph Lateral Scler Frontotemporal Degener. 2022 May;23(3-4):315-319. doi: 10.1080/21678421.2021.1883668. Epub 2021 Mar 8.
ALSUntangled reviews alternative and off-label treatments for people with ALS. Here we review light therapy. We show that it has theoretically plausible mechanisms, three flawed pre-clinical data, studies, and one incompletely documented case report supporting its use. We explain why further studies are needed to determine whether any specific light therapy protocol can help people with ALS.
ALSUntangled 对 ALS 患者的替代和超适应证治疗进行了综述。在这里,我们综述了光疗法。我们表明,它具有理论上合理的机制,但有三项有缺陷的临床前数据、研究和一份支持其使用的不完全记录的病例报告。我们解释了为什么需要进一步研究来确定任何特定的光疗方案是否可以帮助 ALS 患者。