Institute for Marine and Antarctic Studies, University of Tasmania, Launceston, Tas, Australia.
J Fish Dis. 2021 Jul;44(7):1025-1031. doi: 10.1111/jfd.13363. Epub 2021 Mar 8.
Amoebic gill disease (AGD) is a significant issue in Atlantic salmon mariculture. Research on the development of treatments or vaccines uses experimental challenges where salmon is exposed to amoebae concentrations ranging from 500 to 5,000/L. However, the water concentrations of N. perurans on affected salmon farms are much lower. The lowest concentration of N. perurans previously reported to cause AGD was 10/L. Here, we report that concentrations as low as 0.1/L of N. perurans can cause AGD. We propose that concentrations of N. perurans that reflect those measured on salmon farms should be used for future experimental challenges.
阿米巴性鳃病（AGD）是大西洋鲑鱼海水养殖中的一个重大问题。研究治疗方法或疫苗的开发使用了实验性挑战，即在实验中使鲑鱼暴露于浓度为 500 至 5000/L 的变形虫中。然而，受影响的鲑鱼养殖场中的海水尼氏副口吸虫浓度要低得多。先前报道的引起 AGD 的尼氏副口吸虫的最低浓度为 10/L。在这里，我们报告说，尼氏副口吸虫的浓度低至 0.1/L 就可能引起 AGD。我们建议，未来的实验性挑战应使用反映在鲑鱼养殖场中测量到的尼氏副口吸虫浓度。
