妊娠中因副神经节瘤导致缺氧和晕厥：病例报告。

Paraganglioma Presenting as Hypoxia and Syncope in Pregnancy: A Case Report.

机构信息

From the Departments of Obstetrics, Gynecology and Reproductive Sciences.

Endocrinology.

出版信息

A A Pract. 2021 Mar 8;15(3):e01411. doi: 10.1213/XAA.0000000000001411.

DOI:10.1213/XAA.0000000000001411

PMID:33684077

Abstract

Paragangliomas (PGLs) are rare tumors with an incidence of 0.007% in pregnant women. Patients with PGLs commonly present with hypertension and tachycardia. This case report describes the evaluation and management of a multiparous woman at 32 weeks of gestation with syncope, hypoxia, and tachycardia as unusual presenting symptoms of PGL. Her symptoms were attributable to paradoxical effects of circulating catecholamines on downregulated alpha-adrenergic receptors resulting in decreased systemic vascular resistance.

摘要

嗜铬细胞瘤（PGL）是一种罕见的肿瘤，孕妇发病率为 0.007%。PGL 患者常表现为高血压和心动过速。本病例报告描述了一位多产妇在妊娠 32 周时因晕厥、缺氧和心动过速就诊，这些不常见的症状提示 PGL。她的症状归因于循环儿茶酚胺对下调的α-肾上腺素能受体产生的矛盾作用，导致全身血管阻力降低。